biostudies-literatureUnknown4(10)Rajagopal DSalt stress is one of the major factors impacting crop productivity worldwide. Through a variety of effector and signaling pathways, plants achieve survival under salinity stress by maintaining high cytosolic potassium/sodium ion (K⁺/Na⁺) ratios, preventing Na⁺ cytotoxicity, and retaining osmotic balance. Ras-related protein 5 (Rab5) members are involved in the trafficking of endosomes to the vacuole or plasma membrane (PM). The vacuolar protein sorting- associated protein 9 (<i>vps9a</i>) encodes the single guanine nucleotide exchange factor (GEF) that activates all three known Rab5 proteins in <i>Arabidopsis thaliana</i>. Previous work from our group has reported the critical function of <i>vps9a</i> for the operation of salt-induced endocytic pathway, asPlant directe00273https://www.ebi.ac.uk/biostudies/studies/S-EPMC7576885biostudies-literatureRole of <i>Arabidopsis</i> RAB5 GEF <i>vps9a</i> in maintaining potassium levels under sodium chloride stress.PMC7576885Rajagopal DMathew MKfalseRole of <i>Arabidopsis</i> RAB5 GEF <i>vps9a</i> in maintaining potassium levels under sodium chloride stress.Salt stress is one of the major factors impacting crop productivity worldwide. Through a variety of effector and signaling pathways, plants achieve survival under salinity stress by maintaining high cytosolic potassium/sodium ion (K⁺/Na⁺) ratios, preventing Na⁺ cytotoxicity, and retaining osmotic balance. Ras-related protein 5 (Rab5) members are involved in the trafficking of endosomes to the vacuole or plasma membrane (PM). The vacuolar protein sorting- associated protein 9 (<i>vps9a</i>) encodes the single guanine nucleotide exchange factor (GEF) that activates all three known Rab5 proteins in <i>Arabidopsis thaliana</i>. Previous work from our group has reported the critical function of <i>vps9a</i> for the operation of salt-induced endocytic pathway, as2020-01-01T00:00:00Z2020 Oct2025-04-18T15:38:52.744Z2020-10-29T14:51:09ZS-EPMC75768853310304410.1002/pld3.273