biostudies-literatureUnknown170Jagannathan RNational Institute of Diabetes and Digestive and Kidney DiseasesNational Institutes of HealthNational Institute on Minority Health and Health DisparitiesWhether an OGTT reproducibly detects either type 2 diabetes (T2D) or prediabetes in Africans in unknown. Therefore, 131 Africans had two OGTT. Diagnostic reproducibility for T2D was excellent (κ = 0.84), but only moderate for prediabetes (κ = 0.51). A single OGTT positive for T2D may be sufficient to guide clinical care and inform epidemiologic study design. ClinicalTrials.gov Identifier: NCT00001853.Diabetes research and clinical practice108523https://www.ebi.ac.uk/biostudies/studies/S-EPMC7578647biostudies-literatureThe OGTT is highly reproducible in Africans for the diagnosis of diabetes: Implications for treatment and protocol design.PMC7578647Ha JChung STJagannathan RDuBose CWSherman ABergman MSumner AEMabundo LSfalseThe OGTT is highly reproducible in Africans for the diagnosis of diabetes: Implications for treatment and protocol design.Whether an OGTT reproducibly detects either type 2 diabetes (T2D) or prediabetes in Africans in unknown. Therefore, 131 Africans had two OGTT. Diagnostic reproducibility for T2D was excellent (κ = 0.84), but only moderate for prediabetes (κ = 0.51). A single OGTT positive for T2D may be sufficient to guide clinical care and inform epidemiologic study design. ClinicalTrials.gov Identifier: NCT00001853.2020-01-01T00:00:00Z2020 Dec2025-04-04T08:54:55.097Z2024-11-13T23:23:37.448ZS-EPMC75786473315396010.1016/j.diabres.2020.108523