{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Agoti CN"],"funding":["EPA","National Institute for Health Research (NIHR)","Wellcome Trust"],"pagination":["186"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7590893"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["5"],"pubmed_abstract":["<b>Background.</b> International recommendations for the control of the coronavirus disease 2019 (COVID-19) pandemic emphasize the central role of laboratory testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent, at scale. The availability of testing reagents, laboratory equipment and qualified staff are important bottlenecks to achieving this. Elsewhere, pooled testing (i.e. combining multiple samples in the same reaction) has been suggested to increase testing capacities in the pandemic period. <b>Methods.</b> We discuss our experience with SARS-CoV-2 pooled testing using real-time reverse transcription polymerase chain reaction (RT-PCR) on the Kenyan Coast. <b>Results.</b> In mid-May, 2020, our RT-PCR testing capacity for SARS-CoV-2 was improved"],"journal":["Wellcome open research"],"pubmed_title":["Pooled testing conserves SARS-CoV-2 laboratory resources and improves test turn-around time: experience on the Kenyan Coast."],"pmcid":["PMC7590893"],"funding_grant_id":["107568","EP-C-15-003","107568/Z/15/Z","203077","17/63/82","107769"],"pubmed_authors":["Kimani D","Gitonga JN","Lambisia AW","Amadi D","Karani A","Riako D","Bejon P","Mwacharo J","Osoti V","Bartilol B","Mwarumba S","Said Mohammed K","Mugo D","Thoya J","Tsofa B","M Morobe J","Tendwa M","Njuguna S","Tawa B","Ochola-Oyier LI","Gicheru E","de Laurent ZR","Nyamu W","Kiyuka P","Agoti CN","Gumba H","M Gichuki B","Mutua S","Odundo C","Mwangi SJ","Lewa C","Gumbi W","Sein Y","Cheruiyot R","O Omuoyo D","Cheruiyot W","Nyamako L","Otieno E","Mutunga M","Makale J","Musyoki J"],"additional_accession":[]},"is_claimable":false,"name":"Pooled testing conserves SARS-CoV-2 laboratory resources and improves test turn-around time: experience on the Kenyan Coast.","description":"<b>Background.</b> International recommendations for the control of the coronavirus disease 2019 (COVID-19) pandemic emphasize the central role of laboratory testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent, at scale. The availability of testing reagents, laboratory equipment and qualified staff are important bottlenecks to achieving this. Elsewhere, pooled testing (i.e. combining multiple samples in the same reaction) has been suggested to increase testing capacities in the pandemic period. <b>Methods.</b> We discuss our experience with SARS-CoV-2 pooled testing using real-time reverse transcription polymerase chain reaction (RT-PCR) on the Kenyan Coast. <b>Results.</b> In mid-May, 2020, our RT-PCR testing capacity for SARS-CoV-2 was improved","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020","modification":"2025-04-25T22:53:13.591Z","creation":"2020-11-07T11:40:01Z"},"accession":"S-EPMC7590893","cross_references":{"pubmed":["33134555"],"doi":["10.12688/wellcomeopenres.16113.2"]}}