biostudies-literatureUnknown8(19)Mao Z<h4>Background</h4>To assess the association between serum lactate levels and intolerance to enteral nutrition (EN) in septic patients treated with vasopressors.<h4>Methods</h4>This retrospective study was conducted between January 1, 2015 and May 1, 2018 in an intensive care unit (ICU). Patients with sepsis who were given EN and treated with vasopressors were included. EmpowerStats software and R (version 3.3.2) was used to examine the association between serum lactate levels and intolerance to EN.<h4>Results</h4>Among the 132 septic patients (age, 60.6±18.1 years) enrolled, 35 (26.5%) patients suffered intolerance to EN. Multiple logistic regression analysis demonstrated that an elevated lactate level was an independent risk factor for EN intolerance [odds ratio (OR): 2.7; 95% confidenceAnnals of translational medicine1240https://www.ebi.ac.uk/biostudies/studies/S-EPMC7607076biostudies-literatureAssociation between serum lactate levels and enteral feeding intolerance in septic patients treated with vasopressors: a retrospective cohort study.PMC7607076Kang HXue CYu QLou YLi QLiu CZhou FQi SHong QMao ZLiu GfalseAssociation between serum lactate levels and enteral feeding intolerance in septic patients treated with vasopressors: a retrospective cohort study.<h4>Background</h4>To assess the association between serum lactate levels and intolerance to enteral nutrition (EN) in septic patients treated with vasopressors.<h4>Methods</h4>This retrospective study was conducted between January 1, 2015 and May 1, 2018 in an intensive care unit (ICU). Patients with sepsis who were given EN and treated with vasopressors were included. EmpowerStats software and R (version 3.3.2) was used to examine the association between serum lactate levels and intolerance to EN.<h4>Results</h4>Among the 132 septic patients (age, 60.6±18.1 years) enrolled, 35 (26.5%) patients suffered intolerance to EN. Multiple logistic regression analysis demonstrated that an elevated lactate level was an independent risk factor for EN intolerance [odds ratio (OR): 2.7; 95% confidence2020-01-01T00:00:00Z2020 Oct2025-04-26T20:47:24.425Z2025-04-06T16:32:10.034ZS-EPMC76070763317877210.21037/atm-20-6317