{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(19)"],"submitter":["Paraskevas KI"],"pubmed_abstract":["Hypercholesterolemia is a risk factor for carotid artery stenosis and stroke. Statins are the main drugs for the management of hypercholesterolemia and they are strongly recommended by international guidelines for the management of vascular patients. The present review will focus on the associations between cholesterol, carotid artery stenosis and stroke and will cover several topics, including the conservative and perioperative/periprocedural management of carotid patients, the effect of statins on contrast-induced nephropathy developing after endovascular carotid interventions, the role of statin loading prior to endovascular procedures, as well as the indirect beneficial effects of statin treatment on renal function. It will also discuss the topics of statin intolerance and alternative "],"journal":["Annals of translational medicine"],"pagination":["1265"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7607102"],"repository":["biostudies-literature"],"pubmed_title":["Cholesterol, carotid artery disease and stroke: what the vascular specialist needs to know."],"pmcid":["PMC7607102"],"pubmed_authors":["Mikhailidis DP","Ricco JB","Paraskevas KI","Eckstein HH","Veith FJ"],"additional_accession":[]},"is_claimable":false,"name":"Cholesterol, carotid artery disease and stroke: what the vascular specialist needs to know.","description":"Hypercholesterolemia is a risk factor for carotid artery stenosis and stroke. Statins are the main drugs for the management of hypercholesterolemia and they are strongly recommended by international guidelines for the management of vascular patients. The present review will focus on the associations between cholesterol, carotid artery stenosis and stroke and will cover several topics, including the conservative and perioperative/periprocedural management of carotid patients, the effect of statins on contrast-induced nephropathy developing after endovascular carotid interventions, the role of statin loading prior to endovascular procedures, as well as the indirect beneficial effects of statin treatment on renal function. It will also discuss the topics of statin intolerance and alternative ","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Oct","modification":"2025-04-19T23:38:45.084Z","creation":"2025-04-19T23:38:45.084Z"},"accession":"S-EPMC7607102","cross_references":{"pubmed":["33178797"],"doi":["10.21037/atm.2020.02.176"]}}