{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Riga EK"],"funding":["European Research Council"],"pagination":["1800397"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7611512"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["219(23)"],"pubmed_abstract":["Robust, non-delaminating polymer coatings and hydrogels are needed for technical and biomedical applications. This study focusses on surface-attached poly(oxanorbornene) hydrogels obtained by simultaneous UV-activated crosslinking and surface-immobilization. The synthesis and copolymerization of two oxanorbornene monomers carrying the UV-crosslinkers malonic acid diazoester or benzophenone, which can both undergo UV-triggered C,H-insertion crosslinking (CHic), is presented. The crosslinking efficiency and network stability of hydrogels made from these self-crosslinkable polymers are studied and compared to the properties of poly(oxanorbornene) networks obtained by UV-triggered thiol-ene-reactions involving a low molecular weight crosslinker. Smooth, defect-free, non-delaminating hydrogel c"],"journal":["Macromolecular chemistry and physics"],"pubmed_title":["Non-delaminating Polymer Hydrogel Coatings via C,H-Insertion Crosslinking (CHic) - A Case Study of Poly(oxanorbornenes)."],"pmcid":["PMC7611512"],"funding_grant_id":["637920"],"pubmed_authors":["Ruhe J","Riga EK","Lienkamp K"],"additional_accession":[]},"is_claimable":false,"name":"Non-delaminating Polymer Hydrogel Coatings via C,H-Insertion Crosslinking (CHic) - A Case Study of Poly(oxanorbornenes).","description":"Robust, non-delaminating polymer coatings and hydrogels are needed for technical and biomedical applications. This study focusses on surface-attached poly(oxanorbornene) hydrogels obtained by simultaneous UV-activated crosslinking and surface-immobilization. The synthesis and copolymerization of two oxanorbornene monomers carrying the UV-crosslinkers malonic acid diazoester or benzophenone, which can both undergo UV-triggered C,H-insertion crosslinking (CHic), is presented. The crosslinking efficiency and network stability of hydrogels made from these self-crosslinkable polymers are studied and compared to the properties of poly(oxanorbornene) networks obtained by UV-triggered thiol-ene-reactions involving a low molecular weight crosslinker. Smooth, defect-free, non-delaminating hydrogel c","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Dec","modification":"2026-05-08T07:38:36.937Z","creation":"2022-02-11T08:18:06.439Z"},"accession":"S-EPMC7611512","cross_references":{"pubmed":["34404979"],"doi":["10.1002/macp.201800397"]}}