biostudies-literatureVarkey ADBT/Wellcome Trust India AllianceWellcome TrustMars International India Private LimitedTata Trusts3251-3261https://www.ebi.ac.uk/biostudies/studies/S-EPMC7612197biostudies-literatureUnknown39(11)<h4>Background & aims</h4>Stunting in children is a comorbid condition in undernutrition that may be ameliorated by the provision of high-quality foods that provide protein and micronutrients. Addressing this problem in lower social economic environments requires, in part, affordable and scalable food-based solutions with efficacious food products. Towards this end, biochemical/metabolic indicators for fast-throughput screening of foods and their components are desired. A highly acceptable and economical micronutrient-fortified food product with different levels of legume protein was provided to stunted Indian children for one month, to determine change in their linear growth and explore associated biochemical, metabolomic and microbiome indicators.<h4>Methods</h4>A randomized controlled pClinical nutrition (Edinburgh, Scotland)Metabolome and microbiome alterations related to short-term feeding of a micronutrient-fortified, high-quality legume protein-based food product to stunted school age children: A randomized controlled pilot trial.PMC7612197IA/M/14/1/501681Holt RRPauline MVarkey ADevi SAllen LHKeen CLMukhopadhyay AThomas TKurpad AVDharmar MKamat NGfalseMetabolome and microbiome alterations related to short-term feeding of a micronutrient-fortified, high-quality legume protein-based food product to stunted school age children: A randomized controlled pilot trial.<h4>Background & aims</h4>Stunting in children is a comorbid condition in undernutrition that may be ameliorated by the provision of high-quality foods that provide protein and micronutrients. Addressing this problem in lower social economic environments requires, in part, affordable and scalable food-based solutions with efficacious food products. Towards this end, biochemical/metabolic indicators for fast-throughput screening of foods and their components are desired. A highly acceptable and economical micronutrient-fortified food product with different levels of legume protein was provided to stunted Indian children for one month, to determine change in their linear growth and explore associated biochemical, metabolomic and microbiome indicators.<h4>Methods</h4>A randomized controlled p2020-01-01T00:00:00Z2020 Nov2025-04-04T00:38:48.517Z2022-02-11T15:05:10.6ZS-EPMC76121973213911010.1016/j.clnu.2020.02.018