{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Steel A"],"funding":["NIMH internal research program","Intramural NIH HHS","Royal Society","Wellcome Trust"],"pagination":["95-105"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7612345"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["189"],"pubmed_abstract":["Reward and punishment shape behavior, but the mechanisms underlying their effect on skill learning are not well understood. Here, we tested whether the functional connectivity of premotor cortex (PMC), a region known to be critical for learning of sequencing skills, is altered after training when reward or punishment is given during training. Resting-state fMRI was collected in two experiments before and after participants trained on either a serial reaction time task (SRTT; n = 36) or force-tracking task (FTT; n = 36) with reward, punishment, or control feedback. In each experiment, training-related change in PMC functional connectivity was compared across feedback groups. In both tasks, we found that reward and punishment differentially affected PMC functional connectivity. On the SRTT, "],"journal":["NeuroImage"],"pubmed_title":["Differential impact of reward and punishment on functional connectivity after skill learning."],"pmcid":["PMC7612345"],"funding_grant_id":["203139/Z/16/Z","ZIA MH002893","102584","102584/Z/13/Z","ZIA-MH002893"],"pubmed_authors":["Stagg CJ","Baker CI","Steel A","Silson EH"],"additional_accession":[]},"is_claimable":false,"name":"Differential impact of reward and punishment on functional connectivity after skill learning.","description":"Reward and punishment shape behavior, but the mechanisms underlying their effect on skill learning are not well understood. Here, we tested whether the functional connectivity of premotor cortex (PMC), a region known to be critical for learning of sequencing skills, is altered after training when reward or punishment is given during training. Resting-state fMRI was collected in two experiments before and after participants trained on either a serial reaction time task (SRTT; n = 36) or force-tracking task (FTT; n = 36) with reward, punishment, or control feedback. In each experiment, training-related change in PMC functional connectivity was compared across feedback groups. In both tasks, we found that reward and punishment differentially affected PMC functional connectivity. On the SRTT, ","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Apr","modification":"2025-04-21T21:27:36.784Z","creation":"2025-04-05T18:20:25.432Z"},"accession":"S-EPMC7612345","cross_references":{"pubmed":["30630080"],"doi":["10.1016/j.neuroimage.2019.01.009"]}}