biostudies-literatureUnknownMilando CWNIEHS NIH HHSWellcome Trust<h4>Background</h4>Extreme ambient heat is unambiguously associated with higher risk of illness and death. The Optum Labs Data Warehouse (OLDW), a database of medical claims from US-based patients with commercial or Medicare Advantage health insurance, has been used to quantify heat-related health impacts. Whether results for the insured sub-population are generalizable to the broader population has to our knowledge not been documented. We sought to address this question, for the US population in California from 2012 to 2019.<h4>Methods</h4>We examined changes in daily rates of emergency department (ED) encounters and in-patient hospitalization encounters for all-causes, heat-related outcomes, renal disease, mental/behavioral disorders, cardiovascular disease, and respiratory disease. OLDWEpidemiology (Cambridge, Mass.)https://www.ebi.ac.uk/biostudies/studies/S-EPMC7616519biostudies-literatureGeneralizability of heat-related health risk associations observed in a large healthcare claims database of patients with commercial health insurance.PMC7616519216033R01 ES029950Wellenius GAMilando CWRomitti YGause ELSue Wing ISpangler KRSun YNori-Sarma AfalseGeneralizability of heat-related health risk associations observed in a large healthcare claims database of patients with commercial health insurance.<h4>Background</h4>Extreme ambient heat is unambiguously associated with higher risk of illness and death. The Optum Labs Data Warehouse (OLDW), a database of medical claims from US-based patients with commercial or Medicare Advantage health insurance, has been used to quantify heat-related health impacts. Whether results for the insured sub-population are generalizable to the broader population has to our knowledge not been documented. We sought to address this question, for the US population in California from 2012 to 2019.<h4>Methods</h4>We examined changes in daily rates of emergency department (ED) encounters and in-patient hospitalization encounters for all-causes, heat-related outcomes, renal disease, mental/behavioral disorders, cardiovascular disease, and respiratory disease. OLDW2024-01-01T00:00:00Z2024 Aug2025-04-04T08:22:12.319Z2025-04-04T08:22:12.319ZS-EPMC76165193912094910.1097/EDE.0000000000001781