{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["de Araujo TVB"],"funding":["Medical Research Council","Wellcome Trust"],"pagination":["328-336"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7617036"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["18(3)"],"pubmed_abstract":["<h4>Background</h4>A Zika virus epidemic emerged in northeast Brazil in 2015 and was followed by a striking increase in congenital microcephaly cases, triggering a declaration of an international public health emergency. This is the final report of the first case-control study evaluating the potential causes of microcephaly: congenital Zika virus infection, vaccines, and larvicides. The published preliminary report suggested a strong association between microcephaly and congenital Zika virus infection.<h4>Methods</h4>We did a case-control study in eight public maternity hospitals in Recife, Brazil. Cases were neonates born with microcephaly, defined as a head circumference of 2 SD below the mean. Two controls without microcephaly were matched to each case by expected date of delivery and a"],"journal":["The Lancet. Infectious diseases"],"pubmed_title":["Association between microcephaly, Zika virus infection, and other risk factors in Brazil: final report of a case-control study."],"pmcid":["PMC7617036"],"funding_grant_id":["MC_PC_15088","107779"],"pubmed_authors":["Felix Oliveira V","Torres L","Filho SPB","Martelli CMT","Braga C","Castanha PMDS","Bezerra LCA","Evelim Coelho G","Ximenes RAA","Campelo de Albuquerque de Melo CF","Instituto de Medicina Integral Professor Fernando Figueira","Mendez-Rico J","Brazilian Ministry of Health","Dhalia C","Pan American Health Organization","Santos M","Nassri Hazin A","Kleber de Oliveira W","investigators from the Microcephaly Epidemic Research Group","Valongueiro S","Cordeiro MT","Henriques CMP","Dhalia R","Cortez-Escalante JJ","Ismael de Carvalho P","Montarroyos UR","Aldighieri S","Espinal M","Cruz DDCS","State Health Department of Pernambuco","Ramon-Pardo P","Coentro M","Santiago Dimech G","Van der Linden A","de Melo APL","Siqueira de Assuncao R","Marques-Junior ETA","Vazquez E","de Araujo TVB","Miranda-Filho DB","Souza WV","de Albuquerque MFPM","Rodrigues LC","Cortes F"],"additional_accession":[]},"is_claimable":false,"name":"Association between microcephaly, Zika virus infection, and other risk factors in Brazil: final report of a case-control study.","description":"<h4>Background</h4>A Zika virus epidemic emerged in northeast Brazil in 2015 and was followed by a striking increase in congenital microcephaly cases, triggering a declaration of an international public health emergency. This is the final report of the first case-control study evaluating the potential causes of microcephaly: congenital Zika virus infection, vaccines, and larvicides. The published preliminary report suggested a strong association between microcephaly and congenital Zika virus infection.<h4>Methods</h4>We did a case-control study in eight public maternity hospitals in Recife, Brazil. Cases were neonates born with microcephaly, defined as a head circumference of 2 SD below the mean. Two controls without microcephaly were matched to each case by expected date of delivery and a","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Mar","modification":"2026-03-16T08:14:39.846Z","creation":"2025-04-04T00:21:21.972Z"},"accession":"S-EPMC7617036","cross_references":{"pubmed":["29242091"],"doi":["10.1016/s1473-3099(17)30727-2","10.1016/S1473-3099(17)30727-2"]}}