biostudies-literatureTaylor KBritish Heart FoundationUKRI Medical Research CouncilMedical Research CouncilDiabetes UKNational Institute for Health and Care ResearchWellcome Trust558-568https://www.ebi.ac.uk/biostudies/studies/S-EPMC7617111biostudies-literatureUnknown12(8)<h4>Background</h4>Some studies have shown that the incidence of type 2 diabetes increases after a diagnosis of COVID-19, although the evidence is not conclusive. However, the effects of the COVID-19 vaccine on this association, or the effect on other diabetes subtypes, are not clear. We aimed to investigate the association between COVID-19 and incidence of type 2, type 1, gestational and non-specific diabetes, and the effect of COVID- 19 vaccination, up to 52 weeks after diagnosis.<h4>Methods</h4>In this retrospective cohort study, we investigated the diagnoses of incident diabetes following COVID-19 diagnosis in England in a pre-vaccination, vaccinated, and unvaccinated cohort using linked electronic health records. People alive and aged between 18 years and 110 years, registered with a The lancet. Diabetes & endocrinologyIncidence of diabetes after SARS-CoV-2 infection in England and the implications of COVID-19 vaccination: a retrospective cohort study of 16 million people.PMC7617111RG/13/13/30194RE/18/1/34212MC_PC_20059RG/18/13/33946Douglas IFinnigan LCowling TPloubidis GMaddock JGreaves FWilliams DFang CBadrick EGoldacre BTaylor KWielgoszewska BFox LRhead RNigrelli LStewart CLukaschuk EWright JHorne EMFParsons SSmeeth LPatel KSteves CBridger-Staatz CCampbell KCTurner ELNab LMcEachan RHughes AFreydin MSterne JHopcroft LEMForbes HOpenSAFELY collaborativeWalker VBooth CChaturvedi NMcCartney DShah SACONVALESCENCE studyWalter SCarpentieri JSampri AStafford JFisher LGibson ATimpson NKnueppel ACarnemolla ALongitudinal Health and Wellbeing and Data and Connectivity UK COVID-19 National Core StudiesKanagaratnam APerez-Reche FOakley JSheard LHamill Howes LAndrews CMassey JBolton TCuitun Coronado JISheikh AFlaig RLemanska AWei YHamilton OGoncalves Soares AHuntley LZaninotto PShaw RThomas RWillan KWong ADi Gessa GMacleod JMcElroy EGlen FCuitun Coronado JFerreira VWoodward HCurtis HMorley JHorne EKarthikeyan Suseeladevi AAlmaghrabi FGreen ABerman SHerrett EMcLachlan SEastwood SMitchell RMorton CWood AFolarin APiehlmaier DKellas JKnight RGreen MWillans RBeckford CEvans KMZhu JRoberts ACheetham NWhitehorn RRaman BCrane MSanders ZBKromydas TDenaxas SPiechnik SLangan SBrophy SThompson EWang KTunnicliffe EParker MCostello RIp SRafeti ESantorelli GKatikireddi VKibble MDenholm RTeece LBaz SHulme WHopcroft LSilverwood RSaunders LCBoyd AFoster DKwong AGarcia PWild JMMackenna BJones LMoltrecht BSteptoe AYang TGriffith GPark CDavy SMcArdle FDillingham ITazare JTomlinson LAl Arab MRapala AMahalingasivam VSharp SNorth TToms RWalker AZheng BHerbet AJezzard PMansfield KKennedy JIKopasker DNorthstone KJacques WBowyer RRanjan YPalmer TDobson RNeubauer STilling KSterne JACShah ASmith SCampbell AHou BPatalay PCezard GfalseIncidence of diabetes after SARS-CoV-2 infection in England and the implications of COVID-19 vaccination: a retrospective cohort study of 16 million people.<h4>Background</h4>Some studies have shown that the incidence of type 2 diabetes increases after a diagnosis of COVID-19, although the evidence is not conclusive. However, the effects of the COVID-19 vaccine on this association, or the effect on other diabetes subtypes, are not clear. We aimed to investigate the association between COVID-19 and incidence of type 2, type 1, gestational and non-specific diabetes, and the effect of COVID- 19 vaccination, up to 52 weeks after diagnosis.<h4>Methods</h4>In this retrospective cohort study, we investigated the diagnoses of incident diabetes following COVID-19 diagnosis in England in a pre-vaccination, vaccinated, and unvaccinated cohort using linked electronic health records. People alive and aged between 18 years and 110 years, registered with a 2024-01-01T00:00:00Z2024 Aug2025-04-03T23:55:44.937Z2025-04-03T23:55:44.937ZS-EPMC76171113905403410.1016/S2213-8587(24)00159-1