{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kahan BC"],"funding":["Medical Research Council"],"pagination":["2106-2114"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7617336"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["330(21)"],"pubmed_abstract":["<h4>Importance</h4>Transparent reporting of randomized trials is essential to facilitate critical appraisal and interpretation of results. Factorial trials, in which 2 or more interventions are assessed in the same set of participants, have unique methodological considerations. However, reporting of factorial trials is suboptimal.<h4>Objective</h4>To develop a consensus-based extension to the Consolidated Standards of Reporting Trials (CONSORT) 2010 Statement for factorial trials.<h4>Design</h4>Using the Enhancing the Quality and Transparency of Health Research (EQUATOR) methodological framework, the CONSORT extension for factorial trials was developed by (1) generating a list of reporting recommendations for factorial trials using a scoping review of methodological articles identified usi"],"journal":["JAMA"],"pubmed_title":["Reporting of Factorial Randomized Trials: Extension of the CONSORT 2010 Statement."],"pmcid":["PMC7617336"],"funding_grant_id":["MC_UU_00004/07","MR/V020803/1","MC_UU_00004/09"],"pubmed_authors":["Goulao B","Hopewell S","Birchenall M","Chan AW","Fletcher J","Little P","Hall SS","Juszczak E","Beller EM","Kahan BC","Montgomery AA","Golub RM","Elbourne D","Islam N","Zwarenstein M"],"additional_accession":[]},"is_claimable":false,"name":"Reporting of Factorial Randomized Trials: Extension of the CONSORT 2010 Statement.","description":"<h4>Importance</h4>Transparent reporting of randomized trials is essential to facilitate critical appraisal and interpretation of results. Factorial trials, in which 2 or more interventions are assessed in the same set of participants, have unique methodological considerations. However, reporting of factorial trials is suboptimal.<h4>Objective</h4>To develop a consensus-based extension to the Consolidated Standards of Reporting Trials (CONSORT) 2010 Statement for factorial trials.<h4>Design</h4>Using the Enhancing the Quality and Transparency of Health Research (EQUATOR) methodological framework, the CONSORT extension for factorial trials was developed by (1) generating a list of reporting recommendations for factorial trials using a scoping review of methodological articles identified usi","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Dec","modification":"2025-04-04T01:35:48.351Z","creation":"2025-04-04T01:35:48.351Z"},"accession":"S-EPMC7617336","cross_references":{"pubmed":["38051324"],"doi":["10.1001/jama.2023.19793"]}}