{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Nebgen DR"],"funding":["Medical Research Council","National Institute for Health Research (NIHR)"],"pagination":["1437-1450"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7617419"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["130(12)"],"pubmed_abstract":["Women at high inherited risk of ovarian cancer are offered risk-reducing salpingo-oophorectomy (RRSO) from age 35 to 45 years. Although potentially life-saving, RRSO may induce symptoms that negatively affect quality of life and impair long-term health. Clinical care following RRSO is often suboptimal. This scoping review describes how RRSO affects short- and long-term health and provides evidence-based international consensus recommendations for care from preoperative counselling to long-term disease prevention. This includes the efficacy and safety of hormonal and non-hormonal treatments for vasomotor symptoms, sleep disturbance and sexual dysfunction and effective approaches to prevent bone and cardiovascular disease."],"journal":["BJOG : an international journal of obstetrics and gynaecology"],"pubmed_title":["Care after premenopausal risk-reducing salpingo-oophorectomy in high-risk women: Scoping review and international consensus recommendations."],"pmcid":["PMC7617419"],"funding_grant_id":["IS-BRC-1215-20007","NIHR300650","MC_UU_00004/01"],"pubmed_authors":["Crosbie EJ","Brood-van Zanten MMA","Marchetti C","Nebgen DR","Menon U","Kingsberg SA","da Silva Filho AL","Evans DG","Grandi G","Kurian AW","Paramanandam VS","Guise T","Guidozzi F","Domchek SM","Norquist BM","Yuksel N","Kotsopoulos J","Rozenberg S","Bober SL","Johansen N","Hickey M","Brennan DJ","de Hullu JA","Jacobson M","Powell CB","Pederson HJ","Michaelson-Cohen R"],"additional_accession":[]},"is_claimable":false,"name":"Care after premenopausal risk-reducing salpingo-oophorectomy in high-risk women: Scoping review and international consensus recommendations.","description":"Women at high inherited risk of ovarian cancer are offered risk-reducing salpingo-oophorectomy (RRSO) from age 35 to 45 years. Although potentially life-saving, RRSO may induce symptoms that negatively affect quality of life and impair long-term health. Clinical care following RRSO is often suboptimal. This scoping review describes how RRSO affects short- and long-term health and provides evidence-based international consensus recommendations for care from preoperative counselling to long-term disease prevention. This includes the efficacy and safety of hormonal and non-hormonal treatments for vasomotor symptoms, sleep disturbance and sexual dysfunction and effective approaches to prevent bone and cardiovascular disease.","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Nov","modification":"2025-04-18T12:58:33.9Z","creation":"2025-04-06T22:26:05.077Z"},"accession":"S-EPMC7617419","cross_references":{"pubmed":["37132126"],"doi":["10.1111/1471-0528.17511"]}}