{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Pedersen MW"],"funding":["German Research Foundation","Carlsberg Foundation","Gordon and Betty Moore Foundation","Wellcome Trust","Novo Nordisk Fonden","Lundbeck Foundation","National Science Foundation"],"pagination":["2728-2736.e8"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7617452"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["31(12)"],"pubmed_abstract":["Analysis of ancient environmental DNA (eDNA) has revolutionized our ability to describe biological communities in space and time,<sup>1-3</sup> by allowing for parallel sequencing of DNA from all trophic levels.<sup>4-8</sup> However, because environmental samples contain sparse and fragmented data from multiple individuals, and often contain closely related species,<sup>9</sup> the field of ancient eDNA has so far been limited to organellar genomes in its contribution to population and phylogenetic studies.<sup>5</sup><sup>,</sup><sup>6</sup><sup>,</sup><sup>10</sup><sup>,</sup><sup>11</sup> This is in contrast to data from fossils<sup>12</sup><sup>,</sup><sup>13</sup> where full-genome studies are routine, despite these being rare and their destruction for sequencing undesirable.<sup>14-"],"journal":["Current biology : CB"],"pubmed_title":["Environmental genomics of Late Pleistocene black bears and giant short-faced bears."],"pmcid":["PMC7617452"],"funding_grant_id":["207492/Z/17/Z","WT207492","207492","R155-2013-16338","WT220023","NNF18SA0035006","220023","214300/Z/18/Z","R302-2018-2155"],"pubmed_authors":["Heintzman PD","Sikora M","Pedersen MW","Zazula G","Shapiro B","Saremi NF","Vardanyan Z","MacPhee RDE","Gu Z","Vinner L","Cahill JA","Willerslev E","Ardelean CF","Puckett EE","Kapp JD","De Sanctis B","Moon KL","Arroyo-Cabrales J","Durbin R"],"additional_accession":[]},"is_claimable":false,"name":"Environmental genomics of Late Pleistocene black bears and giant short-faced bears.","description":"Analysis of ancient environmental DNA (eDNA) has revolutionized our ability to describe biological communities in space and time,<sup>1-3</sup> by allowing for parallel sequencing of DNA from all trophic levels.<sup>4-8</sup> However, because environmental samples contain sparse and fragmented data from multiple individuals, and often contain closely related species,<sup>9</sup> the field of ancient eDNA has so far been limited to organellar genomes in its contribution to population and phylogenetic studies.<sup>5</sup><sup>,</sup><sup>6</sup><sup>,</sup><sup>10</sup><sup>,</sup><sup>11</sup> This is in contrast to data from fossils<sup>12</sup><sup>,</sup><sup>13</sup> where full-genome studies are routine, despite these being rare and their destruction for sequencing undesirable.<sup>14-","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Jun","modification":"2026-06-01T19:22:50.168Z","creation":"2025-04-07T05:00:03.187Z"},"accession":"S-EPMC7617452","cross_references":{"pubmed":["33878301"],"doi":["10.1016/j.cub.2021.04.027"]}}