{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Afzali M"],"funding":["British Heart Foundation","EPSRC","Wellcome Trust","British Heart Foundation, UK","Engineering and Physical Sciences Research Council"],"pagination":["1022-1034"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7617480"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["92(3)"],"pubmed_abstract":["Purpose
This work reports for the first time on the implementation and application of cardiac diffusion-weighted MRI on a Connectom MR scanner with a maximum gradient strength of 300 mT/m. It evaluates the benefits of the increased gradient performance for the investigation of the myocardial microstructure.Methods
Cardiac diffusion-weighted imaging (DWI) experiments were performed on 10 healthy volunteers using a spin-echo sequence with up to second- and third-order motion compensation ( M2$$ {M}_2 $$ and M3$$ {M}_3 $$ ) and b=100, 450$$ b=100,450 $$ , and 1000 s/mm2$$ \\mathrm{s}/\\mathrm{m}{\\mathrm{m}}^2 $$ (twice the bmax$$ {b}_{\\mathrm{max}} $$ commonly used on clinical scanners). Mean diffusivity (MD), fractional anisotropy (FA), helix angle (HA), and secondary eigenvect"],"journal":["Magnetic resonance in medicine"],"pubmed_title":["In vivo diffusion MRI of the human heart using a 300 mT/m gradient system."],"pmcid":["PMC7617480"],"funding_grant_id":["219536","096646/Z/11/Z","PG/19/1/34076","EP/M029778/1","104943/Z/14/Z","104943","219536/Z/19/Z","096646"],"pubmed_authors":["Schneider JE","Jones DK","Szczepankiewicz F","Afzali M","Fasano F","Mueller L","Coveney S","Evans CJ","Engel M","Teh I","Dall'Armellina E"],"additional_accession":[]},"is_claimable":false,"name":"In vivo diffusion MRI of the human heart using a 300 mT/m gradient system.","description":"Purpose
This work reports for the first time on the implementation and application of cardiac diffusion-weighted MRI on a Connectom MR scanner with a maximum gradient strength of 300 mT/m. It evaluates the benefits of the increased gradient performance for the investigation of the myocardial microstructure.Methods
Cardiac diffusion-weighted imaging (DWI) experiments were performed on 10 healthy volunteers using a spin-echo sequence with up to second- and third-order motion compensation ( M2$$ {M}_2 $$ and M3$$ {M}_3 $$ ) and b=100, 450$$ b=100,450 $$ , and 1000 s/mm2$$ \\mathrm{s}/\\mathrm{m}{\\mathrm{m}}^2 $$ (twice the bmax$$ {b}_{\\mathrm{max}} $$ commonly used on clinical scanners). Mean diffusivity (MD), fractional anisotropy (FA), helix angle (HA), and secondary eigenvect","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Sep","modification":"2026-05-29T19:11:49.542Z","creation":"2026-04-08T05:45:36.63Z"},"accession":"S-EPMC7617480","cross_references":{"pubmed":["38650395"],"doi":["10.1002/mrm.30118"]}}