{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kotronias RA"],"funding":["British Heart Foundation","NIHR Oxford Biomedical Research Centre"],"pagination":["572-585"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7618422"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["18(5)"],"pubmed_abstract":["<h4>Background</h4>Clinical guidelines do not recommend coronary computed tomographic angiography (CTA) in elderly patients or in the presence of heavy coronary calcification. Photon-counting coronary computed tomographic angiography (PCCTA) introduces ultrahigh in-plane resolution and multienergy imaging, but the ability of this technology to overcome these limitations is unclear.<h4>Objectives</h4>The authors evaluate the ability of PCCTA to quantitatively assess coronary luminal stenosis in the presence and absence of calcification, comparing both the ultrahigh-resolution (UHR)-PCCTA and the multienergy standard-resolution (SR)-PCCTA with the criterion-standard 3-dimensional invasive quantitative coronary angiography (3D QCA).<h4>Methods</h4>The authors included 100 patients who had bot"],"journal":["JACC. Cardiovascular imaging"],"pubmed_title":["Benchmarking Photon-Counting Computed Tomography Angiography Against Invasive Assessment of Coronary Stenosis: Implications for Severely Calcified Coronaries."],"pmcid":["PMC7618422"],"funding_grant_id":["CH/F/21/90009","FS/CRTF/23/24460"],"pubmed_authors":["Denton J","Kasongo M","Dawkins S","Hudson B","Rodrigues J","Hatem S","Banning A","Halborg T","Tavildari A","Taylor C","Screaton N","Kelion A","Beer M","Chan K","OxAMI and ORFAN Investigators","Bradlow W","Figtree G","Mehta NN","Fan LJ","Rajani R","Pontone G","Benetos G","Guglielmo M","Shantouf R","Antonopoulos AS","Huck D","Kondo H","Kunadian V","Lin WH","Qin W","Choudhury R","Petersen SE","Antoniades C","Koo BK","Thomas S","Connolly DL","Dweck MR","Benedetti G","Cahill TJ","Deshpande A","Kharbanda RK","Mun MS","Gersh BJ","Santos BS","Sabharwal N","Mavrogiannis MC","Mittal TK","Anthony S","Dai N","Newby DE","Dangas G","Hudson G","de Maria GL","Rodriguez-Granillo GA","Rao P","Preston RL","Ge J","Grenfell R","Kotronias RA","Schmitt M","Vilic D","Bajaj A","Darby D","Maurovich-Horvat P","Danad I","Tousoulis D","Portolan L","Kingham L","Mathers C","Lopez-Jimenez F","Mirsadraee S","Xie C","Aljazzaf H","Graby J","Kietselaer B","Fairbairn TA","Gottlieb I","Holdsworth DA","Berry C","Marwan M","Lawday D","De Bosscher R","Farrall R","Pugliese F","Sharma V","Banning AP","Raisi-Estabragh Z","Neves MF","Kotanidis C","Langrish JP","Serfaty F","Channon KM","Benedek T","Takahashi N","Ledesma C","Selvanayagam J","Walsh J","Neubauer S","Rose A","Das I","Redheuil A","Lucking AJ","He GW"],"additional_accession":[]},"is_claimable":false,"name":"Benchmarking Photon-Counting Computed Tomography Angiography Against Invasive Assessment of Coronary Stenosis: Implications for Severely Calcified Coronaries.","description":"<h4>Background</h4>Clinical guidelines do not recommend coronary computed tomographic angiography (CTA) in elderly patients or in the presence of heavy coronary calcification. Photon-counting coronary computed tomographic angiography (PCCTA) introduces ultrahigh in-plane resolution and multienergy imaging, but the ability of this technology to overcome these limitations is unclear.<h4>Objectives</h4>The authors evaluate the ability of PCCTA to quantitatively assess coronary luminal stenosis in the presence and absence of calcification, comparing both the ultrahigh-resolution (UHR)-PCCTA and the multienergy standard-resolution (SR)-PCCTA with the criterion-standard 3-dimensional invasive quantitative coronary angiography (3D QCA).<h4>Methods</h4>The authors included 100 patients who had bot","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 May","modification":"2026-05-22T03:24:27.749Z","creation":"2026-05-22T03:15:50.955Z"},"accession":"S-EPMC7618422","cross_references":{"pubmed":["39985506"],"doi":["10.1016/j.jcmg.2024.11.005"]}}