biostudies-literatureUnknown12(Suppl 2)Perez-Carbonell LSleep disorders, such as sleep-disordered breathing (SDB), insomnia or restless legs syndrome (RLS), are common in the general population and after stroke. In some cases, sleep disturbances are pre-existing, but can also appear <i>de novo</i> as a direct consequence of brain damage or due to stroke-related complications. Furthermore, some sleep conditions may act as a risk factor of stroke. This review explores the available evidence of the two-way relationship between sleep and stroke. Cardiovascular physiological changes during sleep are described, as well as the evidence on the relationship between stroke and sleep duration, SDB, RLS, insomnia, excessive daytime sleepiness (EDS), and circadian rhythm alterations. Potential changes on sleep architecture, and the links that may exist betwJournal of thoracic diseaseS176-S190https://www.ebi.ac.uk/biostudies/studies/S-EPMC7642629biostudies-literatureNarrative review of sleep and stroke.PMC7642629Perez-Carbonell LBashir SfalseNarrative review of sleep and stroke.Sleep disorders, such as sleep-disordered breathing (SDB), insomnia or restless legs syndrome (RLS), are common in the general population and after stroke. In some cases, sleep disturbances are pre-existing, but can also appear <i>de novo</i> as a direct consequence of brain damage or due to stroke-related complications. Furthermore, some sleep conditions may act as a risk factor of stroke. This review explores the available evidence of the two-way relationship between sleep and stroke. Cardiovascular physiological changes during sleep are described, as well as the evidence on the relationship between stroke and sleep duration, SDB, RLS, insomnia, excessive daytime sleepiness (EDS), and circadian rhythm alterations. Potential changes on sleep architecture, and the links that may exist betw2020-01-01T00:00:00Z2020 Oct2025-04-22T01:16:52.424Z2025-04-05T19:56:36.204ZS-EPMC76426293321492210.21037/jtd-cus-2020-002