biostudies-literatureUnknown12(Suppl 2)Masoud O<h4>Background</h4>Sleep-disordered breathing (SBD) can be associated with hypercapnic respiratory failure (HRF). Home Mechanical Ventilation (HMV) is the preferred long-term treatment for patients with chronic HRF. We reviewed the database of a large tertiary referral centre for HMV to study the long-term adherence to HMV in chronic hypercapnic patients.<h4>Methods</h4>Data on adherence and characteristics of patients who received HMV for the treatment of SDB were collected over a decade using electronic patient records. The primary outcome parameter in this study was annual non-adherence rate (patients with HMV usage of <4 hours/night in the service divided by the number of all new patients of the same year), secondary outcomes were patients' characteristics and reasons for low adherenceJournal of thoracic diseaseS120-S128https://www.ebi.ac.uk/biostudies/studies/S-EPMC7642640biostudies-literatureLong-term adherence to home mechanical ventilation: a 10-year retrospective, single-centre cohort study.PMC7642640Srivastava SHart NRamsay MMarino PKaltsakas GPattani HMasoud OSteier JSuh ESMurphy PBfalseLong-term adherence to home mechanical ventilation: a 10-year retrospective, single-centre cohort study.<h4>Background</h4>Sleep-disordered breathing (SBD) can be associated with hypercapnic respiratory failure (HRF). Home Mechanical Ventilation (HMV) is the preferred long-term treatment for patients with chronic HRF. We reviewed the database of a large tertiary referral centre for HMV to study the long-term adherence to HMV in chronic hypercapnic patients.<h4>Methods</h4>Data on adherence and characteristics of patients who received HMV for the treatment of SDB were collected over a decade using electronic patient records. The primary outcome parameter in this study was annual non-adherence rate (patients with HMV usage of <4 hours/night in the service divided by the number of all new patients of the same year), secondary outcomes were patients' characteristics and reasons for low adherence2020-01-01T00:00:00Z2020 Oct2025-04-22T01:16:58.196Z2025-04-05T19:56:38.216ZS-EPMC76426403321491710.21037/jtd-cus-2020-003