{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bhari VK"],"funding":["Start-up Research","Science and Engineering Research Board","Manipal University Jaipur"],"pagination":["100844"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7643628"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["24"],"pubmed_abstract":["The recent outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has impacted the world severely. The binding of the SARS-CoV-2 virus to the angiotensin-converting enzyme 2 (ACE2) and its intake by the host cell is a necessary step for infection. ACE2 has garnered widespread therapeutic possibility as it is entry/interactive point for SARS-CoV-2, responsible for coronavirus disease 2019 (COVID-19) pandemic and providing a critical regulator for immune modulation in various disease. Patients with suffering from cancer always being on the verge of being immune compromised therefore gaining knowledge about how SARS-CoV-2 viruses affecting immune cells in human cancers will provides us new opportunities for preventing or treating virus-associated cancers. Despite C"],"journal":["Biochemistry and biophysics reports"],"pubmed_title":["SARS-CoV-2 cell receptor gene ACE2 -mediated immunomodulation in breast cancer subtypes."],"pmcid":["PMC7643628"],"funding_grant_id":["SRG/2019/001049","EF/2018-19/QE04-11"],"pubmed_authors":["Kumar D","Bhari VK","Mishra R","Kumar S"],"additional_accession":[]},"is_claimable":false,"name":"SARS-CoV-2 cell receptor gene ACE2 -mediated immunomodulation in breast cancer subtypes.","description":"The recent outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has impacted the world severely. The binding of the SARS-CoV-2 virus to the angiotensin-converting enzyme 2 (ACE2) and its intake by the host cell is a necessary step for infection. ACE2 has garnered widespread therapeutic possibility as it is entry/interactive point for SARS-CoV-2, responsible for coronavirus disease 2019 (COVID-19) pandemic and providing a critical regulator for immune modulation in various disease. Patients with suffering from cancer always being on the verge of being immune compromised therefore gaining knowledge about how SARS-CoV-2 viruses affecting immune cells in human cancers will provides us new opportunities for preventing or treating virus-associated cancers. Despite C","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Dec","modification":"2025-04-04T10:25:28.102Z","creation":"2020-11-09T08:47:41Z"},"accession":"S-EPMC7643628","cross_references":{"pubmed":["33178900"],"doi":["10.1016/j.bbrep.2020.100844"]}}