biostudies-literatureBhari VKStart-up ResearchScience and Engineering Research BoardManipal University Jaipur100844https://www.ebi.ac.uk/biostudies/studies/S-EPMC7643628biostudies-literatureUnknown24The recent outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has impacted the world severely. The binding of the SARS-CoV-2 virus to the angiotensin-converting enzyme 2 (ACE2) and its intake by the host cell is a necessary step for infection. ACE2 has garnered widespread therapeutic possibility as it is entry/interactive point for SARS-CoV-2, responsible for coronavirus disease 2019 (COVID-19) pandemic and providing a critical regulator for immune modulation in various disease. Patients with suffering from cancer always being on the verge of being immune compromised therefore gaining knowledge about how SARS-CoV-2 viruses affecting immune cells in human cancers will provides us new opportunities for preventing or treating virus-associated cancers. Despite CBiochemistry and biophysics reportsSARS-CoV-2 cell receptor gene ACE2 -mediated immunomodulation in breast cancer subtypes.PMC7643628SRG/2019/001049EF/2018-19/QE04-11Kumar DBhari VKMishra RKumar SfalseSARS-CoV-2 cell receptor gene ACE2 -mediated immunomodulation in breast cancer subtypes.The recent outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has impacted the world severely. The binding of the SARS-CoV-2 virus to the angiotensin-converting enzyme 2 (ACE2) and its intake by the host cell is a necessary step for infection. ACE2 has garnered widespread therapeutic possibility as it is entry/interactive point for SARS-CoV-2, responsible for coronavirus disease 2019 (COVID-19) pandemic and providing a critical regulator for immune modulation in various disease. Patients with suffering from cancer always being on the verge of being immune compromised therefore gaining knowledge about how SARS-CoV-2 viruses affecting immune cells in human cancers will provides us new opportunities for preventing or treating virus-associated cancers. Despite C2020-01-01T00:00:00Z2020 Dec2025-04-04T10:25:28.102Z2020-11-09T08:47:41ZS-EPMC76436283317890010.1016/j.bbrep.2020.100844