{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tyson MD"],"funding":["AHRQ HHS","NCI NIH HHS"],"pagination":["26-33"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7643873"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["74(1)"],"pubmed_abstract":["<h4>Background</h4>Whether prostate cancer severity modifies patient-reported functional outcomes after radical prostatectomy (RP) or external beam radiotherapy (EBRT) for localized cancer is unknown.<h4>Objective</h4>The purpose of this study was to determine whether differences in predicted function over time between RP and EBRT varied by risk group.<h4>Design, setting, and participants</h4>The Comparative Effectiveness Analysis of Surgery and Radiation (CEASAR) study is a prospective, population-based, observational study that enrolled men with localized prostate cancer in 2011-2012. Among 2117 CEASAR participants who underwent RP or EBRT, 817 had low-risk, 902 intermediate-risk, and 398 high-risk disease.<h4>Outcome measurements and statistical analysis</h4>Patient-reported, disease-sp"],"journal":["European urology"],"pubmed_title":["Effect of Prostate Cancer Severity on Functional Outcomes After Localized Treatment: Comparative Effectiveness Analysis of Surgery and Radiation Study Results."],"pmcid":["PMC7643873"],"funding_grant_id":["R01 HS019356","R01 HS022640","T32 CA106183"],"pubmed_authors":["Hashibe M","Koyama T","Conwill R","Cooperberg MR","Paddock LE","Goodman M","Tyson MD","Greenfield S","Lee D","Hamilton AS","Resnick MJ","Wu XC","Stroup A","Hoffman KE","Barocas DA","Chen V","McCollum D","Penson DF"],"additional_accession":[]},"is_claimable":false,"name":"Effect of Prostate Cancer Severity on Functional Outcomes After Localized Treatment: Comparative Effectiveness Analysis of Surgery and Radiation Study Results.","description":"<h4>Background</h4>Whether prostate cancer severity modifies patient-reported functional outcomes after radical prostatectomy (RP) or external beam radiotherapy (EBRT) for localized cancer is unknown.<h4>Objective</h4>The purpose of this study was to determine whether differences in predicted function over time between RP and EBRT varied by risk group.<h4>Design, setting, and participants</h4>The Comparative Effectiveness Analysis of Surgery and Radiation (CEASAR) study is a prospective, population-based, observational study that enrolled men with localized prostate cancer in 2011-2012. Among 2117 CEASAR participants who underwent RP or EBRT, 817 had low-risk, 902 intermediate-risk, and 398 high-risk disease.<h4>Outcome measurements and statistical analysis</h4>Patient-reported, disease-sp","dates":{"release":"2018-01-01T00:00:00Z","publication":"2018 Jul","modification":"2025-04-04T01:37:17.394Z","creation":"2020-11-08T09:44:52Z"},"accession":"S-EPMC7643873","cross_references":{"pubmed":["29501451"],"doi":["10.1016/j.eururo.2018.02.012"]}}