{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang S"],"funding":["Natural Science Foundation of Zhejiang Province","National Natural Science Foundation of China"],"pagination":["570844"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7674643"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11"],"pubmed_abstract":["<b>Background and purpose:</b> Midline shift is a life-threatening complication of acute large artery occlusion (LAO). The value of superficial middle cerebral vein (SMCV) for predicting midline shift is currently unclear for patients with acute LAO. <b>Methods:</b> Consecutive acute LAO (middle cerebral artery M1 ± intracranial internal carotid artery) patients between March 2018 and May 2019 were included. Absent filling of ipsilateral cortical vein (marked as SMCV-) was defined as no contrast filling into the vein across the whole venous phase of four-dimensional computed tomography (CT) angiography derived from CT perfusion in the ischemic hemisphere. <b>Results:</b> In the total of 81 patients, 31 (38.4%) were identified as SMCV-. SMCV- independently predicted midline shift, with sensitivity of 87.5% and specificity of 82.5%. Receiver operating characteristic analysis showed that including SMCV- as a predictor in addition to baseline ischemic core volume significantly increased the area under the curve in predicting midline shift (SMCV- with baseline ischemic core volume vs. baseline ischemic core volume: AUC = 0.903 vs. 0.841, <i>Z</i> = 2.451, <i>P</i> = 0.014). <b>Conclusion:</b> In acute LAO patients, the presence of SMCV- was a sensitive and specific imaging marker for midline shift. SMCV- had supplementary value to baseline ischemic core volume in predicting midline shift."],"journal":["Frontiers in neurology"],"pubmed_title":["Absent Contrast Filling of Ipsilateral Superficial Middle Cerebral Vein Predicts Midline Shift in Acute Middle Cerebral Artery Occlusion."],"pmcid":["PMC7674643"],"funding_grant_id":["LQ20H180015"],"pubmed_authors":["Wang M","Parsons M","Geng Y","Zhang S","Shi Z","Lin L","Zhang R","Yu Y"],"additional_accession":[]},"is_claimable":false,"name":"Absent Contrast Filling of Ipsilateral Superficial Middle Cerebral Vein Predicts Midline Shift in Acute Middle Cerebral Artery Occlusion.","description":"<b>Background and purpose:</b> Midline shift is a life-threatening complication of acute large artery occlusion (LAO). The value of superficial middle cerebral vein (SMCV) for predicting midline shift is currently unclear for patients with acute LAO. <b>Methods:</b> Consecutive acute LAO (middle cerebral artery M1 ± intracranial internal carotid artery) patients between March 2018 and May 2019 were included. Absent filling of ipsilateral cortical vein (marked as SMCV-) was defined as no contrast filling into the vein across the whole venous phase of four-dimensional computed tomography (CT) angiography derived from CT perfusion in the ischemic hemisphere. <b>Results:</b> In the total of 81 patients, 31 (38.4%) were identified as SMCV-. SMCV- independently predicted midline shift, with sensitivity of 87.5% and specificity of 82.5%. Receiver operating characteristic analysis showed that including SMCV- as a predictor in addition to baseline ischemic core volume significantly increased the area under the curve in predicting midline shift (SMCV- with baseline ischemic core volume vs. baseline ischemic core volume: AUC = 0.903 vs. 0.841, <i>Z</i> = 2.451, <i>P</i> = 0.014). <b>Conclusion:</b> In acute LAO patients, the presence of SMCV- was a sensitive and specific imaging marker for midline shift. SMCV- had supplementary value to baseline ischemic core volume in predicting midline shift.","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020","modification":"2025-04-27T03:08:21.69Z","creation":"2025-02-19T03:13:17.01Z"},"accession":"S-EPMC7674643","cross_references":{"pubmed":["33224087"],"doi":["10.3389/fneur.2020.570844"]}}