biostudies-literatureUnknown37(5)Bobrowska-Korzeniowska M<h4>Introduction</h4>The usefulness of total specific resistance (sRtot) and interrupter resistance (Rint) as a bronchodilator reversibility test (BT) alternative to forced expiratory volume in 1 s (FEV₁) in asthma diagnosis in children has not been established.<h4>Aim</h4>To compare different applied definitions of airflow obstruction in children measuring response to the bronchodilator by spirometry, plethysmography and the interrupter technique in asthmatic children.<h4>Material and methods</h4>It was a prospective, real-life, non-interventional study. Children, aged 6-18 with newly diagnosed asthma, able to perform lung function tests were included into the study. Subjects underwent a history taking, physical examination, reversibility test in spirometry, plethysmography, anPostepy dermatologii i alergologii685-689https://www.ebi.ac.uk/biostudies/studies/S-EPMC7675071biostudies-literatureUsefulness of sRtot and Rint in bronchodilator testing in the diagnosis of asthma in children.PMC7675071Jerzynska JBobrowska-Korzeniowska MStelmach IBrzozowska AStelmach WfalseUsefulness of sRtot and Rint in bronchodilator testing in the diagnosis of asthma in children.<h4>Introduction</h4>The usefulness of total specific resistance (sRtot) and interrupter resistance (Rint) as a bronchodilator reversibility test (BT) alternative to forced expiratory volume in 1 s (FEV₁) in asthma diagnosis in children has not been established.<h4>Aim</h4>To compare different applied definitions of airflow obstruction in children measuring response to the bronchodilator by spirometry, plethysmography and the interrupter technique in asthmatic children.<h4>Material and methods</h4>It was a prospective, real-life, non-interventional study. Children, aged 6-18 with newly diagnosed asthma, able to perform lung function tests were included into the study. Subjects underwent a history taking, physical examination, reversibility test in spirometry, plethysmography, an2020-01-01T00:00:00Z2020 Oct2025-04-04T10:55:07.745Z2021-02-20T00:54:25ZS-EPMC76750713324000610.5114/ada.2019.85631