{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Oufensou S"],"funding":["Consiglio Nazionale delle Ricerche","Consejo Nacional de Investigaciones Cient?ficas y T?cnicas","Fondo per lo Sviluppo e la Coesione","N? Forschungs- und Bildungsges.m.b.H.","Sipcam Italia S.p.A.","Fondazione di Sardegna"],"pagination":["29407-29415"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7676359"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["5(45)"],"pubmed_abstract":["To assess the in vitro activity of five naturally occurring phenolic compounds (ferulic acid, apocynin, magnolol, honokiol, and thymol) on mycelial growth and type B trichothecene mycotoxin accumulation by <i>Fusarium graminearum</i>, three complementary approaches were adopted. First, a high-throughput photometric continuous reading array allowed a parallel quantification of <i>F. graminearum</i> hyphal growth and reporter <i>TRI5</i> gene expression directly on solid medium. Second, RT-qPCR confirmed the regulation of <i>TRI5</i> expression by the tested compounds. Third, liquid chromatography-tandem mass spectrometry analysis allowed quantification of deoxynivalenol (DON) and its acetylated forms released upon treatment with the phenolic compounds. Altogether, the results confirmed the "],"journal":["ACS omega"],"pubmed_title":["Naturally Occurring Phenols Modulate Vegetative Growth and Deoxynivalenol Biosynthesis in <i>Fusarium graminearum</i>."],"pmcid":["PMC7676359"],"funding_grant_id":["2016-2018","RASSR73282","K3-G-2/026-2013","CUP: J86C16000070009","2016-2019","2017/2018"],"pubmed_authors":["Fabbri D","Dettori MA","Strauss J","Delogu G","Oufensou S","Zehetbauer F","Migheli Q","Balmas V","Schuller C","Azara E"],"additional_accession":[]},"is_claimable":false,"name":"Naturally Occurring Phenols Modulate Vegetative Growth and Deoxynivalenol Biosynthesis in <i>Fusarium graminearum</i>.","description":"To assess the in vitro activity of five naturally occurring phenolic compounds (ferulic acid, apocynin, magnolol, honokiol, and thymol) on mycelial growth and type B trichothecene mycotoxin accumulation by <i>Fusarium graminearum</i>, three complementary approaches were adopted. First, a high-throughput photometric continuous reading array allowed a parallel quantification of <i>F. graminearum</i> hyphal growth and reporter <i>TRI5</i> gene expression directly on solid medium. Second, RT-qPCR confirmed the regulation of <i>TRI5</i> expression by the tested compounds. Third, liquid chromatography-tandem mass spectrometry analysis allowed quantification of deoxynivalenol (DON) and its acetylated forms released upon treatment with the phenolic compounds. Altogether, the results confirmed the ","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Nov","modification":"2025-04-18T21:37:52.581Z","creation":"2025-04-07T09:29:41.206Z"},"accession":"S-EPMC7676359","cross_references":{"pubmed":["33225172"],"doi":["10.1021/acsomega.0c04260"]}}