biostudies-literatureUnknown10(11)Trouillet-Assant S<h4>Introduction</h4>The COVID-19 pandemic caused by SARS-CoV-2 threatens global public health, and there is an urgent public health need to assess acquired immunity to SARS-CoV-2. Serological tests might provide results that can be complementary to or confirm suspected COVID-19 cases and reveal previous infection. The performance of serological assays (sensitivity and specificity) has to be evaluated before their use in the general population. The neutralisation capacity of the produced antibodies also has to be evaluated.<h4>Methods and analysis</h4>We set up a prospective, multicentric clinical study to evaluate the performance of serological kits among a population of healthcare workers presenting mild symptoms suggestive of SARS-CoV-2 infection. Four hundred symptomatic healthcare worBMJ opene041268https://www.ebi.ac.uk/biostudies/studies/S-EPMC7688438biostudies-literatureAssessment of serological techniques for screening patients for COVID-19 (COVID-SER): a prospective, multicentric study.PMC7688438Bal AAdnot JAlfaiate DCotte LFascia PChantal SCaire ESophie TAMarielle PJean-Baptiste FPitiot VNazare JAMakhloufi DTrouillet-Assant SGueyffier FChiarello PMarie-Paule MPaul ACharbotel BDjamila MFrederic MFrancois GIsabelle SMary-Anne TVirginie PD Aubarede CTrabaud MAAdele PAlexandre GBergeret Ad'Aubarede CRabilloud MBruno LBourgeois GBrunel-Dalmas FLucie GDHelene LLahousse MMatthieu GAmelie MPVanessa EAudrey SPascal FJuliette FBonnet FAlbert Vega CNicolas GGuibert NMyriam GMassardier-Pilonchery AMatthieu LDavid NLaurence JDurupt FFatima OBoibieux AJulie-Anne NMuriel RFlorence MCOVID-SER study groupFassier JBSimon CMelanie PfalseAssessment of serological techniques for screening patients for COVID-19 (COVID-SER): a prospective, multicentric study.<h4>Introduction</h4>The COVID-19 pandemic caused by SARS-CoV-2 threatens global public health, and there is an urgent public health need to assess acquired immunity to SARS-CoV-2. Serological tests might provide results that can be complementary to or confirm suspected COVID-19 cases and reveal previous infection. The performance of serological assays (sensitivity and specificity) has to be evaluated before their use in the general population. The neutralisation capacity of the produced antibodies also has to be evaluated.<h4>Methods and analysis</h4>We set up a prospective, multicentric clinical study to evaluate the performance of serological kits among a population of healthcare workers presenting mild symptoms suggestive of SARS-CoV-2 infection. Four hundred symptomatic healthcare wor2020-01-01T00:00:00Z2020 Nov2026-05-04T19:50:13.341Z2021-02-20T03:05:26ZS-EPMC76884383323465110.1136/bmjopen-2020-041268