{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Dobreva T"],"funding":["NINDS NIH HHS"],"pagination":["20540"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7688970"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(1)"],"pubmed_abstract":["An individual's immune system is driven by both genetic and environmental factors that vary over time. To better understand the temporal and inter-individual variability of gene expression within distinct immune cell types, we developed a platform that leverages multiplexed single-cell sequencing and out-of-clinic capillary blood extraction to enable simplified, cost-effective profiling of the human immune system across people and time at single-cell resolution. Using the platform, we detect widespread differences in cell type-specific gene expression between subjects that are stable over multiple days."],"journal":["Scientific reports"],"pubmed_title":["Single cell profiling of capillary blood enables out of clinic human immunity studies."],"pmcid":["PMC7688970"],"funding_grant_id":["T32 NS105595"],"pubmed_authors":["Park JH","Thomson M","Dobreva T","Brown D"],"additional_accession":[]},"is_claimable":false,"name":"Single cell profiling of capillary blood enables out of clinic human immunity studies.","description":"An individual's immune system is driven by both genetic and environmental factors that vary over time. To better understand the temporal and inter-individual variability of gene expression within distinct immune cell types, we developed a platform that leverages multiplexed single-cell sequencing and out-of-clinic capillary blood extraction to enable simplified, cost-effective profiling of the human immune system across people and time at single-cell resolution. Using the platform, we detect widespread differences in cell type-specific gene expression between subjects that are stable over multiple days.","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Nov","modification":"2025-04-27T02:55:50.035Z","creation":"2021-02-21T04:54:08Z"},"accession":"S-EPMC7688970","cross_references":{"pubmed":["33239690"],"doi":["10.1038/s41598-020-77073-3"]}}