{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hill J"],"funding":["Bill and Melinda Gates Foundation"],"pagination":["433"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7690090"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["19(1)"],"pubmed_abstract":["<h4>Background</h4>Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended for preventing malaria in pregnancy in areas of moderate-to-high transmission in sub-Saharan Africa. However, due to increasing parasite resistance to SP, research on alternative strategies is a priority. The study assessed the implementation feasibility of intermittent screening and treatment (ISTp) in the second and third trimester at antenatal care (ANC) with malaria rapid diagnostic tests (RDTs) and treatment of positive cases with dihydroartemisinin-piperaquine (DP) compared to IPTp-SP in western Kenya.<h4>Methods</h4>A 10-month implementation study was conducted in 12 government health facilities in four sub-counties. Six health facilities were assigned to eithe"],"journal":["Malaria journal"],"pubmed_title":["Intermittent screening and treatment with dihydroartemisinin-piperaquine for the prevention of malaria in pregnancy: implementation feasibility in a routine healthcare system setting in western Kenya."],"pmcid":["PMC7690090"],"funding_grant_id":["OPP46099"],"pubmed_authors":["Oluoch S","Bruce J","Desai M","Webster J","Ouma P","Hill J","Kariuki S"],"additional_accession":[]},"is_claimable":false,"name":"Intermittent screening and treatment with dihydroartemisinin-piperaquine for the prevention of malaria in pregnancy: implementation feasibility in a routine healthcare system setting in western Kenya.","description":"<h4>Background</h4>Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended for preventing malaria in pregnancy in areas of moderate-to-high transmission in sub-Saharan Africa. However, due to increasing parasite resistance to SP, research on alternative strategies is a priority. The study assessed the implementation feasibility of intermittent screening and treatment (ISTp) in the second and third trimester at antenatal care (ANC) with malaria rapid diagnostic tests (RDTs) and treatment of positive cases with dihydroartemisinin-piperaquine (DP) compared to IPTp-SP in western Kenya.<h4>Methods</h4>A 10-month implementation study was conducted in 12 government health facilities in four sub-counties. Six health facilities were assigned to eithe","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Nov","modification":"2026-05-28T11:26:12.719Z","creation":"2025-02-19T03:26:42.739Z"},"accession":"S-EPMC7690090","cross_references":{"pubmed":["33238999"],"doi":["10.1186/s12936-020-03505-0"]}}