{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(11)"],"submitter":["Taghipour A"],"pubmed_abstract":["Although the cause of multiple sclerosis (MS) is unclear, infectious agents, including some parasitic roundworms (nematodes), have been proposed as possible risk factors or contributors. Here, we conducted a systematic review and meta-analysis of published observational studies to evaluate whether there is a possible association between infection with, or exposure to, one or more members of the genus Toxocara (phylum Nematoda; superfamily Ascaridoidea) and MS. We undertook a search of public literature databases to identify relevant studies and then used a random-effects meta-analysis model to generate the pooled odds ratio (OR) and 95% confidence intervals (CIs). This search identified six of a total of 1371 articles that were relevant to the topic; these published studies involved totals"],"journal":["Pathogens (Basel, Switzerland)"],"pagination":["E938"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7696196"],"repository":["biostudies-literature"],"pubmed_title":["\"Begging the Question\"-Does Toxocara Infection/Exposure Associate with Multiple Sclerosis-Risk?"],"pmcid":["PMC7696196"],"pubmed_authors":["Nicoletti A","Gasser RB","Rostami A","Esfandyari S","Aghapour S","Taghipour A"],"additional_accession":[]},"is_claimable":false,"name":"\"Begging the Question\"-Does Toxocara Infection/Exposure Associate with Multiple Sclerosis-Risk?","description":"Although the cause of multiple sclerosis (MS) is unclear, infectious agents, including some parasitic roundworms (nematodes), have been proposed as possible risk factors or contributors. Here, we conducted a systematic review and meta-analysis of published observational studies to evaluate whether there is a possible association between infection with, or exposure to, one or more members of the genus Toxocara (phylum Nematoda; superfamily Ascaridoidea) and MS. We undertook a search of public literature databases to identify relevant studies and then used a random-effects meta-analysis model to generate the pooled odds ratio (OR) and 95% confidence intervals (CIs). This search identified six of a total of 1371 articles that were relevant to the topic; these published studies involved totals","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Nov","modification":"2025-04-22T05:28:50.455Z","creation":"2025-04-05T21:20:23.066Z"},"accession":"S-EPMC7696196","cross_references":{"pubmed":["33187271"],"doi":["10.3390/pathogens9110938"]}}