{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hammerling S"],"funding":["Deutsche Forschungsgemeinschaft"],"pagination":["14377-14384"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7702172"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["26(63)"],"pubmed_abstract":["The dimethylchloronium salt [Me<sub>2</sub> Cl][Al(OTeF<sub>5</sub> )<sub>4</sub> ] is used to methylate electron-deficient aromatic systems in Friedel-Crafts type reactions as shown by the synthesis of N-methylated cations, such as [MeNC<sub>5</sub> F<sub>5</sub> ]<sup>+</sup> , [MeNC<sub>5</sub> F<sub>4</sub> I]<sup>+</sup> , and [MeN<sub>3</sub> C<sub>3</sub> F<sub>3</sub> ]<sup>+</sup> . To gain a better understanding of such fundamental Friedel-Crafts reactions, the role of the dimethylchloronium cation has been evaluated by quantum-chemical calculations."],"journal":["Chemistry (Weinheim an der Bergstrasse, Germany)"],"pubmed_title":["Friedel-Crafts Type Methylation with Dimethylhalonium Salts."],"pmcid":["PMC7702172"],"funding_grant_id":["387284271"],"pubmed_authors":["Hammerling S","Voßnacker P","Steinhauer S","Riedel S","Beckers H"],"additional_accession":[]},"is_claimable":false,"name":"Friedel-Crafts Type Methylation with Dimethylhalonium Salts.","description":"The dimethylchloronium salt [Me<sub>2</sub> Cl][Al(OTeF<sub>5</sub> )<sub>4</sub> ] is used to methylate electron-deficient aromatic systems in Friedel-Crafts type reactions as shown by the synthesis of N-methylated cations, such as [MeNC<sub>5</sub> F<sub>5</sub> ]<sup>+</sup> , [MeNC<sub>5</sub> F<sub>4</sub> I]<sup>+</sup> , and [MeN<sub>3</sub> C<sub>3</sub> F<sub>3</sub> ]<sup>+</sup> . To gain a better understanding of such fundamental Friedel-Crafts reactions, the role of the dimethylchloronium cation has been evaluated by quantum-chemical calculations.","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Nov","modification":"2025-04-05T10:52:55.989Z","creation":"2025-04-05T10:52:55.989Z"},"accession":"S-EPMC7702172","cross_references":{"pubmed":["32277527"],"doi":["10.1002/chem.202001457"]}}