{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Massaoudi Y"],"funding":["Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii"],"pagination":["8852418"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7707988"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["2020"],"pubmed_abstract":["Recently, the implication of oxidative stress in behavioral-like disorders has received a lot of attention. Many studies were interested in searching for new natural compounds with protective effects on behavioral-like disorders by focusing on oxidative stress as the main causal factor. Here, we assess the potential effect of cell-free extracts from halophilic bacteria on memory, anxiety, and depression-related behaviors in mice, as well as on cognitive deficits, negative symptoms, and some oxidative stress biomarkers in methionine-induced mice models of schizophrenia. Firstly, crude extracts of bacteria isolated from the Dead Sea were screened for their effects on memory and anxiety- and depression-like behaviors through Y-maze, elevated plus maze, and forced swimming test, respectively, "],"journal":["Evidence-based complementary and alternative medicine : eCAM"],"pubmed_title":["Protective Effects of Two Halophilic Crude Extracts from <i>Pseudomonas zhaodongensis</i> and <i>Bacillus stratosphericus</i> against Memory Deficits and Anxiety- and Depression-Like Behaviors in Methionine-Induced Schizophrenia in Mice Focusing on Oxidative Stress Status."],"pmcid":["PMC7707988"],"funding_grant_id":["PN-III-P1-1.1-TE-2016-1210"],"pubmed_authors":["Sendide K","Anissi J","Ciobica A","Massaoudi Y","Lefter R","Hassouni ME","Lobiuc A"],"additional_accession":[]},"is_claimable":false,"name":"Protective Effects of Two Halophilic Crude Extracts from <i>Pseudomonas zhaodongensis</i> and <i>Bacillus stratosphericus</i> against Memory Deficits and Anxiety- and Depression-Like Behaviors in Methionine-Induced Schizophrenia in Mice Focusing on Oxidative Stress Status.","description":"Recently, the implication of oxidative stress in behavioral-like disorders has received a lot of attention. Many studies were interested in searching for new natural compounds with protective effects on behavioral-like disorders by focusing on oxidative stress as the main causal factor. Here, we assess the potential effect of cell-free extracts from halophilic bacteria on memory, anxiety, and depression-related behaviors in mice, as well as on cognitive deficits, negative symptoms, and some oxidative stress biomarkers in methionine-induced mice models of schizophrenia. Firstly, crude extracts of bacteria isolated from the Dead Sea were screened for their effects on memory and anxiety- and depression-like behaviors through Y-maze, elevated plus maze, and forced swimming test, respectively, ","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020","modification":"2025-04-18T11:31:41.044Z","creation":"2021-02-20T10:35:30Z"},"accession":"S-EPMC7707988","cross_references":{"pubmed":["33299461"],"doi":["10.1155/2020/8852418"]}}