biostudies-literatureUnknown12(11)Chen X<h4>Background</h4>Transcervical esophagectomy is a less invasive procedure performed within mediastinum. However, the mediastinum offers limited surgical space and the surgery via this route differs from conventional minimally invasive esophagectomy. Therefore, the physiological study of this surgical approach on an animal model would be necessary before the procedure gained more popularity.<h4>Methods</h4>We conducted transcervical minimally invasive esophagectomy on animal model (swine) under CO₂ pneumomediastinum. The hemodynamic parameters were monitored using float catheter cannulated via right jugular vein. At different anatomical level (the upper, middle, and lower thoracic part of the animal esophagus), increased artificial pneumomediastinal pressures (0, 4, 8, 12, and Journal of thoracic disease6505-6513https://www.ebi.ac.uk/biostudies/studies/S-EPMC7711368biostudies-literatureTranscervical minimally invasive esophagectomy: hemodynamic study on an animal model.PMC7711368Liu XTan LXue SLin GChen XShen YXu JZhong MfalseTranscervical minimally invasive esophagectomy: hemodynamic study on an animal model.<h4>Background</h4>Transcervical esophagectomy is a less invasive procedure performed within mediastinum. However, the mediastinum offers limited surgical space and the surgery via this route differs from conventional minimally invasive esophagectomy. Therefore, the physiological study of this surgical approach on an animal model would be necessary before the procedure gained more popularity.<h4>Methods</h4>We conducted transcervical minimally invasive esophagectomy on animal model (swine) under CO₂ pneumomediastinum. The hemodynamic parameters were monitored using float catheter cannulated via right jugular vein. At different anatomical level (the upper, middle, and lower thoracic part of the animal esophagus), increased artificial pneumomediastinal pressures (0, 4, 8, 12, and 2020-01-01T00:00:00Z2020 Nov2025-04-04T23:46:38.983Z2025-04-04T23:46:38.983ZS-EPMC77113683328235210.21037/jtd-20-1905