{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang X"],"funding":["Auburn University College of Veterinary Medicine","US National Science Foundation","Alabama Agricultural Experiment Station (AAES) ARES Agriculture Research Enhancement, Exploration and Development","National Science Foundation EPSCoR RII Track-4 Research Fellowship","Auburn University Intramural","USDA National Institute of Food and Agriculture Hatch","Auburn University Presidential Graduate Research Fellowship and Auburn University College of Veterinary Medicine Dean’s Fellowship","Nathaniel and Helen Wisch Professorship"],"pagination":["2508-2520"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7719230"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(12)"],"pubmed_abstract":["Wolbachia are widespread intracellular bacteria that mediate many important biological processes in arthropod species. In this study, we identified 210 conserved single-copy genes in 33 genome-sequenced Wolbachia strains in the A-F supergroups. Phylogenomic analyses with these core genes indicate that all 33 Wolbachia strains maintain the supergroup relationship, which was classified previously based on the multilocus sequence typing (MLST) genes. Using an interclade recombination screening method, 14 inter-supergroup recombination events were discovered in six genes (2.9%) among 210 single-copy orthologs. This finding suggests a relatively low frequency of intergroup recombination. Interestingly, they have occurred not only between A and B supergroups (nine events) but also between A and "],"journal":["Genome biology and evolution"],"pubmed_title":["Phylogenomic Analysis of Wolbachia Strains Reveals Patterns of Genome Evolution and Recombination."],"pmcid":["PMC7719230"],"funding_grant_id":["AUIGP-180271","1950078","1018100","1456233","NSF OIA 1928770"],"pubmed_authors":["Cao W","Wang X","Zhang C","Werren JH","Xiong X"],"additional_accession":[]},"is_claimable":false,"name":"Phylogenomic Analysis of Wolbachia Strains Reveals Patterns of Genome Evolution and Recombination.","description":"Wolbachia are widespread intracellular bacteria that mediate many important biological processes in arthropod species. In this study, we identified 210 conserved single-copy genes in 33 genome-sequenced Wolbachia strains in the A-F supergroups. Phylogenomic analyses with these core genes indicate that all 33 Wolbachia strains maintain the supergroup relationship, which was classified previously based on the multilocus sequence typing (MLST) genes. Using an interclade recombination screening method, 14 inter-supergroup recombination events were discovered in six genes (2.9%) among 210 single-copy orthologs. This finding suggests a relatively low frequency of intergroup recombination. Interestingly, they have occurred not only between A and B supergroups (nine events) but also between A and ","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Dec","modification":"2025-05-29T22:30:43.364Z","creation":"2025-05-29T22:30:43.364Z"},"accession":"S-EPMC7719230","cross_references":{"pubmed":["33283864"],"doi":["10.1093/gbe/evaa219"]}}