biostudies-literatureUnknown11(1)Mayer R<h4>Background</h4>Prostate tumor volume correlates with critical components of cancer staging such as Gleason score (GS) grade, predicted disease progression, and metastasis. Therefore, non-invasive tumor volume measurement may elevate clinical management. Radiology assessments of multi-parametric MRI (MP-MRI) commonly visually examine individual images to determine possible tumor presence. This study combines registered MP-MRI into a single image that display normal tissue and possible lesions. This study tests and exploits the vector nature of spatially registered MP-MRI by using supervised target detection algorithms (STDA) and color display and psychovisual analysis (CIELAB) to non-invasively estimate prostate tumor volume.<h4>Methods</h4>MRI, including T1, T2, diffusion [apparent difQuantitative imaging in medicine and surgery119-132https://www.ebi.ac.uk/biostudies/studies/S-EPMC7719922biostudies-literatureAlgorithms applied to spatially registered multi-parametric MRI for prostate tumor volume measurement.PMC7719922Turkbey BChoyke PSimone CBMayer RfalseAlgorithms applied to spatially registered multi-parametric MRI for prostate tumor volume measurement.<h4>Background</h4>Prostate tumor volume correlates with critical components of cancer staging such as Gleason score (GS) grade, predicted disease progression, and metastasis. Therefore, non-invasive tumor volume measurement may elevate clinical management. Radiology assessments of multi-parametric MRI (MP-MRI) commonly visually examine individual images to determine possible tumor presence. This study combines registered MP-MRI into a single image that display normal tissue and possible lesions. This study tests and exploits the vector nature of spatially registered MP-MRI by using supervised target detection algorithms (STDA) and color display and psychovisual analysis (CIELAB) to non-invasively estimate prostate tumor volume.<h4>Methods</h4>MRI, including T1, T2, diffusion [apparent dif2021-01-01T00:00:00Z2021 Jan2025-06-01T02:17:43.959Z2021-02-20T19:43:25ZS-EPMC77199223339201610.21037/qims-20-137a