{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang PH"],"funding":["Ministry of Health and Welfare"],"pagination":["21367"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7721715"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(1)"],"pubmed_abstract":["A significantly negative reversion in the QuantiFERON-TB Gold In-tube (QFT-GIT) test is reported in patients on dialysis, which makes the results unreliable. The CD4 and CD8 responses of the QFT-Gold plus (QFT-Plus) may have better positive consistency, but this needs to be investigated. We enrolled dialysis patients with baseline positive QFT-GIT<sub>0</sub> results and conducted two rounds of follow-up paired QFT-GIT<sub>1&2</sub> and QFT-Plus<sub>1&2</sub> tests at an interval of 6 months. The positive consistency, concordance, and discordance of the QFT results were analyzed. A total of 236 patients on dialysis were screened, and 73 participants with positive QFT-GIT<sub>0</sub> results were enrolled. The baseline QFT-GIT<sub>0</sub> response was higher in the 1st QFT-Plus<sub>1</sub>("],"journal":["Scientific reports"],"pubmed_title":["CD4 response of QuantiFERON-TB Gold Plus for positive consistency of latent tuberculosis infection in patients on dialysis."],"pmcid":["PMC7721715"],"funding_grant_id":["107-TDU-B-211-123002, 108-TDU-B-211-133002"],"pubmed_authors":["Yu CJ","Shu CC","Wang PH","Lee CY","Wei YF","Lin SW","Lee SS","Wang JY","Lin SY"],"additional_accession":[]},"is_claimable":false,"name":"CD4 response of QuantiFERON-TB Gold Plus for positive consistency of latent tuberculosis infection in patients on dialysis.","description":"A significantly negative reversion in the QuantiFERON-TB Gold In-tube (QFT-GIT) test is reported in patients on dialysis, which makes the results unreliable. The CD4 and CD8 responses of the QFT-Gold plus (QFT-Plus) may have better positive consistency, but this needs to be investigated. We enrolled dialysis patients with baseline positive QFT-GIT<sub>0</sub> results and conducted two rounds of follow-up paired QFT-GIT<sub>1&2</sub> and QFT-Plus<sub>1&2</sub> tests at an interval of 6 months. The positive consistency, concordance, and discordance of the QFT results were analyzed. A total of 236 patients on dialysis were screened, and 73 participants with positive QFT-GIT<sub>0</sub> results were enrolled. The baseline QFT-GIT<sub>0</sub> response was higher in the 1st QFT-Plus<sub>1</sub>(","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Dec","modification":"2025-04-26T14:45:07.699Z","creation":"2025-04-06T14:40:47.73Z"},"accession":"S-EPMC7721715","cross_references":{"pubmed":["33288814"],"doi":["10.1038/s41598-020-78374-3"]}}