{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Atkinson N"],"funding":["Leverhulme Trust","RCUK | Biotechnology and Biological Sciences Research Council","Wellcome Trust","Biotechnology and Biological Sciences Research Council"],"pagination":["6303"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7726157"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(1)"],"pubmed_abstract":["Photosynthetic CO<sub>2</sub> fixation in plants is limited by the inefficiency of the CO<sub>2</sub>-assimilating enzyme Rubisco. In most eukaryotic algae, Rubisco aggregates within a microcompartment known as the pyrenoid, in association with a CO<sub>2</sub>-concentrating mechanism that improves photosynthetic operating efficiency under conditions of low inorganic carbon. Recent work has shown that the pyrenoid matrix is a phase-separated, liquid-like condensate. In the alga Chlamydomonas reinhardtii, condensation is mediated by two components: Rubisco and the linker protein EPYC1 (Essential Pyrenoid Component 1). Here, we show that expression of mature EPYC1 and a plant-algal hybrid Rubisco leads to spontaneous condensation of Rubisco into a single phase-separated compartment in Arabid"],"journal":["Nature communications"],"pubmed_title":["Condensation of Rubisco into a proto-pyrenoid in higher plant chloroplasts."],"pmcid":["PMC7726157"],"funding_grant_id":["RPG-2017-402","BB/S015337/1","WT104915MA","BB/S015531/1"],"pubmed_authors":["Atkinson N","McCormick AJ","Chan KX","Mao Y"],"additional_accession":[]},"is_claimable":false,"name":"Condensation of Rubisco into a proto-pyrenoid in higher plant chloroplasts.","description":"Photosynthetic CO<sub>2</sub> fixation in plants is limited by the inefficiency of the CO<sub>2</sub>-assimilating enzyme Rubisco. In most eukaryotic algae, Rubisco aggregates within a microcompartment known as the pyrenoid, in association with a CO<sub>2</sub>-concentrating mechanism that improves photosynthetic operating efficiency under conditions of low inorganic carbon. Recent work has shown that the pyrenoid matrix is a phase-separated, liquid-like condensate. In the alga Chlamydomonas reinhardtii, condensation is mediated by two components: Rubisco and the linker protein EPYC1 (Essential Pyrenoid Component 1). Here, we show that expression of mature EPYC1 and a plant-algal hybrid Rubisco leads to spontaneous condensation of Rubisco into a single phase-separated compartment in Arabid","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Dec","modification":"2025-04-22T13:40:47.78Z","creation":"2025-04-06T00:42:05.882Z"},"accession":"S-EPMC7726157","cross_references":{"pubmed":["33298923"],"doi":["10.1038/s41467-020-20132-0"]}}