biostudies-literatureUnknown15(12)Hou T<h4>Purposes</h4>Since a considerable number of health care workers (HCWs) were sent to Wuhan to aid COVID-19 control during the epidemic, non-frontline HCWs who stayed in local hospitals had to work overload to provide daily health care services for other health issues, which makes them more vulnerable to experience fatigue. Self-efficacy is suggested as a protective factor for fatigue. Nonetheless, less is known regarding the underlying mechanisms. This research aimed to explore the prevalence of fatigue among non-frontline HCWs during the pandemic, investigate the mediating effect of posttraumatic stress disorder (PTSD) symptoms and moderating effect of negative coping in the association between self-efficacy and fatigue.<h4>Methods</h4>General Self-Efficacy Scale, PTSD Checklist-CiviliPloS onee0243884https://www.ebi.ac.uk/biostudies/studies/S-EPMC7728176biostudies-literatureSelf-efficacy and fatigue among non-frontline health care workers during COVID-19 outbreak: A moderated mediation model of posttraumatic stress disorder symptoms and negative coping.PMC7728176Zhang FLiu YDong WHou TSong XZhang RDeng GCai WfalseSelf-efficacy and fatigue among non-frontline health care workers during COVID-19 outbreak: A moderated mediation model of posttraumatic stress disorder symptoms and negative coping.<h4>Purposes</h4>Since a considerable number of health care workers (HCWs) were sent to Wuhan to aid COVID-19 control during the epidemic, non-frontline HCWs who stayed in local hospitals had to work overload to provide daily health care services for other health issues, which makes them more vulnerable to experience fatigue. Self-efficacy is suggested as a protective factor for fatigue. Nonetheless, less is known regarding the underlying mechanisms. This research aimed to explore the prevalence of fatigue among non-frontline HCWs during the pandemic, investigate the mediating effect of posttraumatic stress disorder (PTSD) symptoms and moderating effect of negative coping in the association between self-efficacy and fatigue.<h4>Methods</h4>General Self-Efficacy Scale, PTSD Checklist-Civili2020-01-01T00:00:00Z20202025-04-19T08:14:24.09Z2025-04-19T08:14:24.09ZS-EPMC77281763330152310.1371/journal.pone.0243884