{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(22)"],"submitter":["Yang X"],"pubmed_abstract":["Intraoperative floppy iris syndrome (IFIS) is characterized by intraoperative floppiness or billowing of the iris, progressive miosis, and iris prolapse through the surgical wounds. It was originally reported about fifteen years ago, which was later identified to be closely associated with tamsulosin, the most commonly used α1 adrenoceptor antagonist for benign prostatic hyperplasia (BPH). A variety of risk factors, including age, gender, hypertension, axial length of the eye, 5α-reductase inhibitors, other α adrenoceptor antagonist and neuromodulators, have been connected with IFIS. If IFIS occurs during phacoemulsification surgery, complications such as corneal endothelial loss, iris trauma, posterior capsule rupture (PCR), high intraocular pressure and vitreous loss are significantly in"],"journal":["Annals of translational medicine"],"pagination":["1546"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7729334"],"repository":["biostudies-literature"],"pubmed_title":["A narrative review of intraoperative floppy iris syndrome: an update 2020."],"pmcid":["PMC7729334"],"pubmed_authors":["Yang X","Grzybowski A","Wang N","Liu Z","Fan Z"],"additional_accession":[]},"is_claimable":false,"name":"A narrative review of intraoperative floppy iris syndrome: an update 2020.","description":"Intraoperative floppy iris syndrome (IFIS) is characterized by intraoperative floppiness or billowing of the iris, progressive miosis, and iris prolapse through the surgical wounds. It was originally reported about fifteen years ago, which was later identified to be closely associated with tamsulosin, the most commonly used α1 adrenoceptor antagonist for benign prostatic hyperplasia (BPH). A variety of risk factors, including age, gender, hypertension, axial length of the eye, 5α-reductase inhibitors, other α adrenoceptor antagonist and neuromodulators, have been connected with IFIS. If IFIS occurs during phacoemulsification surgery, complications such as corneal endothelial loss, iris trauma, posterior capsule rupture (PCR), high intraocular pressure and vitreous loss are significantly in","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Nov","modification":"2025-04-04T23:46:34.453Z","creation":"2025-04-04T23:46:34.453Z"},"accession":"S-EPMC7729334","cross_references":{"pubmed":["33313291"],"doi":["10.21037/atm-20-3214"]}}