biostudies-literatureAimagambetova GNazarbayev Universitye0242024https://www.ebi.ac.uk/biostudies/studies/S-EPMC7735622biostudies-literatureUnknown15(12)<h4>Introduction</h4>Infertility is a problem that affects millions of people worldwide. The aim of this study was to assess the effect of stress, depression and anxiety on the IVF outcomes in Kazakhstan.<h4>Methods</h4>The prospective cohort study was performed using questionnaires to assess psychological distress in 304 infertile female in three different cities in Kazakhstan.<h4>Results</h4>The average age of participants was 33.7 years with infertility duration of 5.9 years. Regarding stress, depression and anxiety we found that more than 80% of all respondents had CES-D score higher than 16, indicating that they are at risk of developing clinical depression. On average, FPI subscales' scores, global stress score and anxiety scale (STAI-S and STAI-T) scores were statistically significaPloS oneThe effect of psychological distress on IVF outcomes: Reality or speculations?PMC7735622Social policy grantBapayeva GIssanov AUkybassova TBaikoshkarova SAimagambetova GTerzic MShauyen FTerzic SAldiyarova AfalseThe effect of psychological distress on IVF outcomes: Reality or speculations?<h4>Introduction</h4>Infertility is a problem that affects millions of people worldwide. The aim of this study was to assess the effect of stress, depression and anxiety on the IVF outcomes in Kazakhstan.<h4>Methods</h4>The prospective cohort study was performed using questionnaires to assess psychological distress in 304 infertile female in three different cities in Kazakhstan.<h4>Results</h4>The average age of participants was 33.7 years with infertility duration of 5.9 years. Regarding stress, depression and anxiety we found that more than 80% of all respondents had CES-D score higher than 16, indicating that they are at risk of developing clinical depression. On average, FPI subscales' scores, global stress score and anxiety scale (STAI-S and STAI-T) scores were statistically significa2020-01-01T00:00:00Z20202025-04-26T09:09:20.002Z2025-04-06T12:55:17.807ZS-EPMC77356223331587810.1371/journal.pone.0242024