{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7"],"submitter":["Sun JT"],"pubmed_abstract":["<b>Background:</b> Emerging studies have described and analyzed epidemiological, clinical, laboratory, and radiological features of COVID-19 patients. Yet, scarce information is available regarding the association of lipid profile features and disease severity and mortality. <b>Methods:</b> We conducted a prospective observational cohort study to investigate lipid profile features in patients with COVID-19. From 9 February to 4 April 2020, a total of 99 patients (31 critically ill and 20 severely ill) with confirmed COVID-19 were included in the study. Dynamic alterations in lipid profiles were recorded and tracked. Outcomes were followed up until 4 April 2020. <b>Results:</b> We found that high-density lipoprotein-cholesterol (HDL-C) and apolipoprotein A-1 (apoA-1) levels were significant"],"journal":["Frontiers in cardiovascular medicine"],"pagination":["584987"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7746652"],"repository":["biostudies-literature"],"pubmed_title":["Lipid Profile Features and Their Associations With Disease Severity and Mortality in Patients With COVID-19."],"pmcid":["PMC7746652"],"pubmed_authors":["Shen L","Chen Z","Nie P","Ge H","Pu J","Wang W","Zhang M","Sun JT","Qu XL","Ying XY","Zhou Y","Yang F"],"additional_accession":[]},"is_claimable":false,"name":"Lipid Profile Features and Their Associations With Disease Severity and Mortality in Patients With COVID-19.","description":"<b>Background:</b> Emerging studies have described and analyzed epidemiological, clinical, laboratory, and radiological features of COVID-19 patients. Yet, scarce information is available regarding the association of lipid profile features and disease severity and mortality. <b>Methods:</b> We conducted a prospective observational cohort study to investigate lipid profile features in patients with COVID-19. From 9 February to 4 April 2020, a total of 99 patients (31 critically ill and 20 severely ill) with confirmed COVID-19 were included in the study. Dynamic alterations in lipid profiles were recorded and tracked. Outcomes were followed up until 4 April 2020. <b>Results:</b> We found that high-density lipoprotein-cholesterol (HDL-C) and apolipoprotein A-1 (apoA-1) levels were significant","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020","modification":"2025-06-01T00:20:31.415Z","creation":"2025-06-01T00:20:31.415Z"},"accession":"S-EPMC7746652","cross_references":{"pubmed":["33344516"],"doi":["10.3389/fcvm.2020.584987"]}}