{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["39(5)"],"submitter":["Zhong Y"],"pubmed_abstract":["Although the direct health impact of Coronavirus disease (COVID-19) pandemic on child health is low, there are indirect impacts across many aspects. We compare childhood vaccine uptake in three types of healthcare facilities in Singapore - public primary care clinics, a hospital paediatric unit, and private paediatrician clinics - from January to April 2020, to baseline, and calculate the impact on herd immunity for measles. We find a 25.6% to 73.6% drop in Measles-Mumps-Rubella (MMR) uptake rates, 0.4 - 10.3% drop for Diphtheria-Tetanus-Pertussis-inactivated Polio-Haemophilus influenza (5-in-1), and 8.0-67.8% drop for Pneumococcal conjugate vaccine (PCV) across all 3 sites. Consequent herd immunity reduces to 74-84% among 12-month- to 2-year-olds, well below the 95% coverage that is protective for measles. This puts the whole community at risk for a measles epidemic. Public health efforts are urgently needed to maintain efficacious coverage for routine childhood vaccines during the COVID-19 pandemic."],"journal":["Vaccine"],"pagination":["780-785"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7762701"],"repository":["biostudies-literature"],"pubmed_title":["Childhood vaccinations: Hidden impact of COVID-19 on children in Singapore."],"pmcid":["PMC7762701"],"pubmed_authors":["Chiang WC","Lee BW","Clapham HE","Murugasu B","Chua YX","Ong M","Chin HL","Mathews J","Zhong Y","Aishworiya R","Wang J"],"additional_accession":[]},"is_claimable":false,"name":"Childhood vaccinations: Hidden impact of COVID-19 on children in Singapore.","description":"Although the direct health impact of Coronavirus disease (COVID-19) pandemic on child health is low, there are indirect impacts across many aspects. We compare childhood vaccine uptake in three types of healthcare facilities in Singapore - public primary care clinics, a hospital paediatric unit, and private paediatrician clinics - from January to April 2020, to baseline, and calculate the impact on herd immunity for measles. We find a 25.6% to 73.6% drop in Measles-Mumps-Rubella (MMR) uptake rates, 0.4 - 10.3% drop for Diphtheria-Tetanus-Pertussis-inactivated Polio-Haemophilus influenza (5-in-1), and 8.0-67.8% drop for Pneumococcal conjugate vaccine (PCV) across all 3 sites. Consequent herd immunity reduces to 74-84% among 12-month- to 2-year-olds, well below the 95% coverage that is protective for measles. This puts the whole community at risk for a measles epidemic. Public health efforts are urgently needed to maintain efficacious coverage for routine childhood vaccines during the COVID-19 pandemic.","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Jan","modification":"2024-11-08T10:27:34.355Z","creation":"2021-02-21T01:12:56Z"},"accession":"S-EPMC7762701","cross_references":{"pubmed":["33414050"],"doi":["10.1016/j.vaccine.2020.12.054"]}}