{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Broome DT"],"funding":["NIDDK NIH HHS","National Institutes of Health"],"pagination":["237-250"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7765647"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["106(1)"],"pubmed_abstract":["Maturity-onset diabetes of the young, or MODY-monogenic diabetes, is a not-so-rare collection of inherited disorders of non-autoimmune diabetes mellitus that remains insufficiently diagnosed despite increasing awareness. These cases are important to efficiently and accurately diagnose, given the clinical implications of syndromic features, cost-effective treatment regimen, and the potential impact on multiple family members. Proper recognition of the clinical manifestations, family history, and cost-effective lab and genetic testing provide the diagnosis. All patients must undergo a thorough history, physical examination, multigenerational family history, lab evaluation (glycated hemoglobin A1c [HbA1c], glutamic acid decarboxylase antibodies [GADA], islet antigen 2 antibodies [IA-2A], and "],"journal":["The Journal of clinical endocrinology and metabolism"],"pubmed_title":["Approach to the Patient with MODY-Monogenic Diabetes."],"pmcid":["PMC7765647"],"funding_grant_id":["R01DK104942","P30 DK020595","R01 DK104942","P30DK020595","U54 DK118612","DK118612-01"],"pubmed_authors":["Kashyap SR","Philipson LH","Pantalone KM","Broome DT"],"additional_accession":[]},"is_claimable":false,"name":"Approach to the Patient with MODY-Monogenic Diabetes.","description":"Maturity-onset diabetes of the young, or MODY-monogenic diabetes, is a not-so-rare collection of inherited disorders of non-autoimmune diabetes mellitus that remains insufficiently diagnosed despite increasing awareness. These cases are important to efficiently and accurately diagnose, given the clinical implications of syndromic features, cost-effective treatment regimen, and the potential impact on multiple family members. Proper recognition of the clinical manifestations, family history, and cost-effective lab and genetic testing provide the diagnosis. All patients must undergo a thorough history, physical examination, multigenerational family history, lab evaluation (glycated hemoglobin A1c [HbA1c], glutamic acid decarboxylase antibodies [GADA], islet antigen 2 antibodies [IA-2A], and ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Jan","modification":"2025-04-04T03:40:13.128Z","creation":"2022-02-11T11:59:56.005Z"},"accession":"S-EPMC7765647","cross_references":{"pubmed":["33034350"],"doi":["10.1210/clinem/dgaa710"]}}