{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["34(1)"],"submitter":["Ghazaleh S"],"pubmed_abstract":["<h4>Background</h4>The role of anticoagulation in treating non-malignant portal vein (PV) thrombosis (PVT) in patients with liver cirrhosis remains unclear. In our meta-analysis, we aimed to evaluate the efficacy and safety of anticoagulation for the treatment of non-malignant PVT in these patients.<h4>Methods</h4>We conducted a meta-analysis to estimate the effects of anticoagulation on non-malignant PVT in patients with liver cirrhosis. We assessed the rates of PV recanalization, variceal bleeding, and any bleeding.<h4>Results</h4>We included 9 observational studies which involved 474 patients. The rate of PV recanalization was significantly higher in patients who received anticoagulation compared to those who did not: 65.2% vs. 25.2%; relative risk (RR) 2.31, 95% confidence interval (CI"],"journal":["Annals of gastroenterology"],"pagination":["104-110"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7774659"],"repository":["biostudies-literature"],"pubmed_title":["Efficacy and safety of anticoagulation in non-malignant portal vein thrombosis in patients with liver cirrhosis: a systematic review and meta-analysis."],"pmcid":["PMC7774659"],"pubmed_authors":["Nehme C","Khader Y","Aburayyan K","Patel D","Sharma S","Aziz M","Abdel-Aziz Y","Beran A","Ghazaleh S","Nawras A","Hammad T"],"additional_accession":[]},"is_claimable":false,"name":"Efficacy and safety of anticoagulation in non-malignant portal vein thrombosis in patients with liver cirrhosis: a systematic review and meta-analysis.","description":"<h4>Background</h4>The role of anticoagulation in treating non-malignant portal vein (PV) thrombosis (PVT) in patients with liver cirrhosis remains unclear. In our meta-analysis, we aimed to evaluate the efficacy and safety of anticoagulation for the treatment of non-malignant PVT in these patients.<h4>Methods</h4>We conducted a meta-analysis to estimate the effects of anticoagulation on non-malignant PVT in patients with liver cirrhosis. We assessed the rates of PV recanalization, variceal bleeding, and any bleeding.<h4>Results</h4>We included 9 observational studies which involved 474 patients. The rate of PV recanalization was significantly higher in patients who received anticoagulation compared to those who did not: 65.2% vs. 25.2%; relative risk (RR) 2.31, 95% confidence interval (CI","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2025-04-26T06:34:51.444Z","creation":"2025-04-06T11:53:38.138Z"},"accession":"S-EPMC7774659","cross_references":{"pubmed":["33414629"],"doi":["10.20524/aog.2020.0544"]}}