{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang L"],"funding":["NIBIB NIH HHS","Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill","Department of Radiology, University of North Carolina at Chapel Hill","Biomedical Research Imaging Center, University of North Carolina at Chapel Hill","National Institute of Biomedical Imaging and Bioengineering"],"pagination":["7971-7975"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7774802"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["22(20)"],"pubmed_abstract":["Herein, we describe an organic photoredox system for direct arene C-H radiofluorination, using a peroxide oxidizing agent and LEDs as the light source. In conjunction with an optimized photocatalyst and a microtubing reactor, this system is applicable to a range of electron-rich aromatics and heteroaromatics. We also demonstrate the feasibility of C-H radiofluorination without an azeotropic drying step, which greatly simplifies the workflow of the labeling process."],"journal":["Organic letters"],"pubmed_title":["Direct Radiofluorination of Arene C-H Bonds via Photoredox Catalysis Using a Peroxide as the Terminal Oxidant."],"pmcid":["PMC7774802"],"funding_grant_id":["R01 EB029451","1R01EB029451"],"pubmed_authors":["Wu Z","Li Z","White AR","Chen W","Wang L","Nicewicz DA"],"additional_accession":[]},"is_claimable":false,"name":"Direct Radiofluorination of Arene C-H Bonds via Photoredox Catalysis Using a Peroxide as the Terminal Oxidant.","description":"Herein, we describe an organic photoredox system for direct arene C-H radiofluorination, using a peroxide oxidizing agent and LEDs as the light source. In conjunction with an optimized photocatalyst and a microtubing reactor, this system is applicable to a range of electron-rich aromatics and heteroaromatics. We also demonstrate the feasibility of C-H radiofluorination without an azeotropic drying step, which greatly simplifies the workflow of the labeling process.","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Oct","modification":"2024-11-20T10:26:06.53Z","creation":"2022-02-11T12:11:22.927Z"},"accession":"S-EPMC7774802","cross_references":{"pubmed":["33000949"],"doi":["10.1021/acs.orglett.0c02815"]}}