{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8"],"submitter":["Bardanzellu F"],"pubmed_abstract":["<b>Introduction:</b> In premature neonates, the persistence of hemodynamically significant ductus arteriosus (hsPDA) can be associated with short- and long-term consequences, impairing their outcome. The correct strategy of management for such condition is under debate, especially regarding contraindications and/or side effects. In recent years, metabolomics was applied to several perinatal, pediatric, and adult conditions to investigate potential biomarkers of disease, which have become useful for early diagnosis and/or therapeutic management. <b>Aim of the Study:</b> The main purpose of our exploratory study was to asses, through <sup>1</sup>H-NMR metabolomics analysis of urinary samples at birth, possible metabolic pathways differentiating, with a significant predictive power, those pre"],"journal":["Frontiers in pediatrics"],"pagination":["613749"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7779766"],"repository":["biostudies-literature"],"pubmed_title":["Early Urinary Metabolomics in Patent Ductus Arteriosus Anticipates the Fate: Preliminary Data."],"pmcid":["PMC7779766"],"pubmed_authors":["Atzei A","Fanos V","Bardanzellu F","Neroni P","Piras C"],"additional_accession":[]},"is_claimable":false,"name":"Early Urinary Metabolomics in Patent Ductus Arteriosus Anticipates the Fate: Preliminary Data.","description":"<b>Introduction:</b> In premature neonates, the persistence of hemodynamically significant ductus arteriosus (hsPDA) can be associated with short- and long-term consequences, impairing their outcome. The correct strategy of management for such condition is under debate, especially regarding contraindications and/or side effects. In recent years, metabolomics was applied to several perinatal, pediatric, and adult conditions to investigate potential biomarkers of disease, which have become useful for early diagnosis and/or therapeutic management. <b>Aim of the Study:</b> The main purpose of our exploratory study was to asses, through <sup>1</sup>H-NMR metabolomics analysis of urinary samples at birth, possible metabolic pathways differentiating, with a significant predictive power, those pre","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020","modification":"2026-07-09T10:58:48.099Z","creation":"2026-07-09T10:35:05.151Z"},"accession":"S-EPMC7779766","cross_references":{"pubmed":["33409262"],"doi":["10.3389/fped.2020.613749"]}}