biostudies-literatureUnknown8Jacobson KJapan Tobacco International, SwitzerlandSeveral regulatory initiatives around the world restrict the amount of nicotine permitted in electronic cigarette liquids in an attempt to reproduce the nicotine delivery of combusted tobacco products, such as cigarettes, and or reduce the risk of consumers absorbing too much nicotine into their body at one time. Such an approach, however, assumes that (i) there is a strong correlation between the levels of nicotine in electronic cigarette liquids and nicotine intake into the body and (ii) that this correlation holds true across the various different types of electronic cigarette devices currently available on the market. In order to test these hypotheses, this study examines the available scientific literature on nicotine intake from electronic cigarettes, as measured by levels in the bloToxicology reports84-95https://www.ebi.ac.uk/biostudies/studies/S-EPMC7786013biostudies-literatureNicotine pharmacokinetics of electronic cigarettes: A pooled data analysis from the literature.PMC7786013Martinez JJones IWPaschke TJacobson KLarroque SfalseNicotine pharmacokinetics of electronic cigarettes: A pooled data analysis from the literature.Several regulatory initiatives around the world restrict the amount of nicotine permitted in electronic cigarette liquids in an attempt to reproduce the nicotine delivery of combusted tobacco products, such as cigarettes, and or reduce the risk of consumers absorbing too much nicotine into their body at one time. Such an approach, however, assumes that (i) there is a strong correlation between the levels of nicotine in electronic cigarette liquids and nicotine intake into the body and (ii) that this correlation holds true across the various different types of electronic cigarette devices currently available on the market. In order to test these hypotheses, this study examines the available scientific literature on nicotine intake from electronic cigarettes, as measured by levels in the blo2021-01-01T00:00:00Z20212025-05-31T23:01:12.61Z2025-05-31T23:01:12.61ZS-EPMC77860133343765110.1016/j.toxrep.2020.12.016