{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(23)"],"submitter":["Deng Z"],"pubmed_abstract":["Stem cell-based therapy is a promising treatment for cartilage defects due to the pluripotency, abundant sources and low immunogenicity of stem cells. Hydrogels are a promising class of biomaterials for cartilage engineering and are characterized by bioactivity, degradability and elasticity as well as provide water content and mechanical support. The combination of stem cells and hydrogels opens new possibilities for cartilage tissue engineering. However, the selection of suitable types of stem cells and hydrogels is difficult. Currently, various types of stem cells, such as embryonic stem cells (ESCs), mesenchymal stem cells (MSCs), induced pluripotent stem cells (iPSCs), and peripheral blood mononuclear cells (PBMSCs), and various types of hydrogels, including natural polymers, chemicall"],"journal":["Annals of translational medicine"],"pagination":["1598"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7791208"],"repository":["biostudies-literature"],"pubmed_title":["Narrative review of the choices of stem cell sources and hydrogels for cartilage tissue engineering."],"pmcid":["PMC7791208"],"pubmed_authors":["Li Y","Wang S","Deng Z","Qi F","Ma Y","Lyu F","Zheng Q","Chen X","Liu C","Jin J"],"additional_accession":[]},"is_claimable":false,"name":"Narrative review of the choices of stem cell sources and hydrogels for cartilage tissue engineering.","description":"Stem cell-based therapy is a promising treatment for cartilage defects due to the pluripotency, abundant sources and low immunogenicity of stem cells. Hydrogels are a promising class of biomaterials for cartilage engineering and are characterized by bioactivity, degradability and elasticity as well as provide water content and mechanical support. The combination of stem cells and hydrogels opens new possibilities for cartilage tissue engineering. However, the selection of suitable types of stem cells and hydrogels is difficult. Currently, various types of stem cells, such as embryonic stem cells (ESCs), mesenchymal stem cells (MSCs), induced pluripotent stem cells (iPSCs), and peripheral blood mononuclear cells (PBMSCs), and various types of hydrogels, including natural polymers, chemicall","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Dec","modification":"2025-04-05T16:11:17.609Z","creation":"2025-04-05T16:11:17.609Z"},"accession":"S-EPMC7791208","cross_references":{"pubmed":["33437797"],"doi":["10.21037/atm-20-2342"]}}