biostudies-literatureGarg PWellcome TrustAcademy of Medical Sciencese001448https://www.ebi.ac.uk/biostudies/studies/S-EPMC7802648biostudies-literatureUnknown8(1)<h4>Objectives</h4>To characterise and risk-stratify patients presenting to a heart failure (HF) clinic according to the National Institute for health and Care Excellence (NICE) algorithm.<h4>Methods</h4>This is an observational study of prospectively collected data in the Sheffield HEArt Failure registry of consecutive patients with suspected HF between April 2012 and January 2020. Outcome was defined as all-cause mortality.<h4>Results</h4>6144 patients were enrolled: 71% had HF and 29% had no HF. Patients with N-terminal pro-brain-type natriuretic peptide (NT-proBNP) >2000 pg/mL were more likely to have HF than those with NT-proBNP of 400-2000 pg/mL (92% vs 64%, respectively). Frequency of HF phenotypes include: HF with preserved ejection fraction (HFpEF) (33%), HF with reduced ejection Open heartCharacterisation of the patients with suspected heart failure: experience from the SHEAF registry.PMC7802648205188/Z/16/ZAS: 205188/Z/16/ZSGL018\1100Swift AJAl-Mohammad AAssadi HNaveed ULewis NFent GGarg PCharalampopoulos ARogers DDakshi AfalseCharacterisation of the patients with suspected heart failure: experience from the SHEAF registry.<h4>Objectives</h4>To characterise and risk-stratify patients presenting to a heart failure (HF) clinic according to the National Institute for health and Care Excellence (NICE) algorithm.<h4>Methods</h4>This is an observational study of prospectively collected data in the Sheffield HEArt Failure registry of consecutive patients with suspected HF between April 2012 and January 2020. Outcome was defined as all-cause mortality.<h4>Results</h4>6144 patients were enrolled: 71% had HF and 29% had no HF. Patients with N-terminal pro-brain-type natriuretic peptide (NT-proBNP) >2000 pg/mL were more likely to have HF than those with NT-proBNP of 400-2000 pg/mL (92% vs 64%, respectively). Frequency of HF phenotypes include: HF with preserved ejection fraction (HFpEF) (33%), HF with reduced ejection 2021-01-01T00:00:00Z2021 Jan2026-07-16T00:39:36.09Z2026-07-09T10:26:32.048ZS-EPMC78026483343161710.1136/openhrt-2020-001448