{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Odgis JA"],"funding":["NICHD NIH HHS","NCATS NIH HHS","NHGRI NIH HHS","National Human Genome Research Institute"],"pagination":["56"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7807444"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["22(1)"],"pubmed_abstract":["<h4>Background</h4>Increasingly, genomics is informing clinical practice, but challenges remain for medical professionals lacking genetics expertise, and in access to and clinical utility of genomic testing for minority and underrepresented populations. The latter is a particularly pernicious problem due to the historical lack of inclusion of racially and ethnically diverse populations in genomic research and genomic medicine. A further challenge is the rapidly changing landscape of genetic tests and considerations of cost, interpretation, and diagnostic yield for emerging modalities like whole-genome sequencing.<h4>Methods</h4>The NYCKidSeq project is a randomized controlled trial recruiting 1130 children and young adults predominantly from Harlem and the Bronx with suspected genetic diso"],"journal":["Trials"],"pubmed_title":["The NYCKidSeq project: study protocol for a randomized controlled trial incorporating genomics into the clinical care of diverse New York City children."],"pmcid":["PMC7807444"],"funding_grant_id":["U01HG009610","U01 HG009610","UL1 TR002556","P50 HD105352"],"pubmed_authors":["Aguiniga KL","Watnick D","Wolf SM","Horowitz CR","Blackburn C","Bauman LJ","McDonald TV","Maria E","Kelly NR","Rhodes R","Fielding L","Lopez J","Bertier G","Stolte C","Yozawitz E","Rubinstein A","Gallagher KM","Suckiel SA","Rinke ML","Wasserstein MP","Rodriguez JE","Kovatch P","Bloom T","Cunningham-Rundles C","Jobanputra V","Ferket BS","Robinson M","Teitelman N","Kenny EE","Zinberg RE","McGoldrick PE","Greally JM","Yelton NM","Odgis JA","Dolan S","Abul-Husn NS","Abhyankar A","Donohue KE","Sebastin M","Baum A","Brown K","Beal JC","Ramos MA","Gelb BD","Shulman LH","Diaz GA"],"additional_accession":[]},"is_claimable":false,"name":"The NYCKidSeq project: study protocol for a randomized controlled trial incorporating genomics into the clinical care of diverse New York City children.","description":"<h4>Background</h4>Increasingly, genomics is informing clinical practice, but challenges remain for medical professionals lacking genetics expertise, and in access to and clinical utility of genomic testing for minority and underrepresented populations. The latter is a particularly pernicious problem due to the historical lack of inclusion of racially and ethnically diverse populations in genomic research and genomic medicine. A further challenge is the rapidly changing landscape of genetic tests and considerations of cost, interpretation, and diagnostic yield for emerging modalities like whole-genome sequencing.<h4>Methods</h4>The NYCKidSeq project is a randomized controlled trial recruiting 1130 children and young adults predominantly from Harlem and the Bronx with suspected genetic diso","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Jan","modification":"2026-04-18T01:08:29.936Z","creation":"2021-02-21T10:43:42Z"},"accession":"S-EPMC7807444","cross_references":{"pubmed":["33446240"],"doi":["10.1186/s13063-020-04953-4"]}}