{"database":"biostudies-literature","file_versions":[],"scores":{"citationCount":0,"reanalysisCount":0,"viewCount":56,"searchCount":0},"additional":{"submitter":["Thorwarth D"],"funding":["German Research Council"],"pagination":["69-73"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7807787"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16"],"pubmed_abstract":["Many preclinical and clinical observations support that functional magnetic resonance imaging (MRI), such as diffusion weighted (DW) and dynamic contrast enhanced (DCE) MRI, might have a predictive value for radiotherapy. The aim of this review was to assess the current status of quantitative MRI on hybrid MR-Linacs. In a literature research, four publications were identified, investigating technical feasibility, accuracy, repeatability and reproducibility of DW and DCE-MRI in phantoms and first patients. Accuracy and short term repeatability was < 5% for DW-MRI in current MR-Linac systems. Consequently, quantitative imaging providing accurate and reproducible functional information seems possible in MR-Linacs."],"journal":["Physics and imaging in radiation oncology"],"pubmed_title":["Quantitative magnetic resonance imaging on hybrid magnetic resonance linear accelerators: Perspective on technical and clinical validation."],"pmcid":["PMC7807787"],"funding_grant_id":["TH 1528/6-1","GA 2996/1-1","ZI 736/2-1","ZI 736/4-1"],"pubmed_authors":["Monnich D","Thorwarth D","Boeke S","Zips D","Nachbar M","Gani C","Ege M"],"view_count":["56"],"additional_accession":[]},"is_claimable":false,"name":"Quantitative magnetic resonance imaging on hybrid magnetic resonance linear accelerators: Perspective on technical and clinical validation.","description":"Many preclinical and clinical observations support that functional magnetic resonance imaging (MRI), such as diffusion weighted (DW) and dynamic contrast enhanced (DCE) MRI, might have a predictive value for radiotherapy. The aim of this review was to assess the current status of quantitative MRI on hybrid MR-Linacs. In a literature research, four publications were identified, investigating technical feasibility, accuracy, repeatability and reproducibility of DW and DCE-MRI in phantoms and first patients. Accuracy and short term repeatability was < 5% for DW-MRI in current MR-Linac systems. Consequently, quantitative imaging providing accurate and reproducible functional information seems possible in MR-Linacs.","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Oct","modification":"2024-12-03T18:21:53.479Z","creation":"2021-02-21T00:02:24Z"},"accession":"S-EPMC7807787","cross_references":{"pubmed":["33458346"],"doi":["10.1016/j.phro.2020.09.007"]}}