biostudies-literatureUnknown128(2)de Ruigh AA<h4>Objective</h4>To assess the effect of transabdominal amnioinfusion or no intervention on long-term outcomes in children born after second-trimester prelabour rupture of the membranes (PROM between 16^+0/7 -24^+0/7  weeks) and oligohydramnios.<h4>Population</h4>Follow up of infants of women who participated in the randomised controlled trial: PPROMEXIL-III (NTR3492).<h4>Methods</h4>Surviving infants were invited for neurodevelopmental assessment up to 5 years of corrected age using a Bayley Scales of Infant and Toddler Development or a Wechsler Preschool and Primary Scale of Intelligence. Parents were asked to complete several questionnaires.<h4>Main outcome measures</h4>Neurodevelopmental outcomes were measured. Mild delay was defined as -1 standard deviation (SD), BJOG : an international journal of obstetrics and gynaecology292-301https://www.ebi.ac.uk/biostudies/studies/S-EPMC7818451biostudies-literatureChild outcomes after amnioinfusion compared with no intervention in women with second-trimester rupture of membranes: a long-term follow-up study of the PROMEXIL-III trial.PMC7818451Woiski Mvan Teeffelen ASvan Kempen LSimons NEde Ruigh AAOepkes Dvan Wassenaer-Leemhuis AGPajkrt EAarnoudse-Moens Cvan 't Hooft Jvan de Beek CRoseboom TJDerks JBMol BWPorath MMHaak MCDuijnhoven RGfalseChild outcomes after amnioinfusion compared with no intervention in women with second-trimester rupture of membranes: a long-term follow-up study of the PROMEXIL-III trial.<h4>Objective</h4>To assess the effect of transabdominal amnioinfusion or no intervention on long-term outcomes in children born after second-trimester prelabour rupture of the membranes (PROM between 16^+0/7 -24^+0/7  weeks) and oligohydramnios.<h4>Population</h4>Follow up of infants of women who participated in the randomised controlled trial: PPROMEXIL-III (NTR3492).<h4>Methods</h4>Surviving infants were invited for neurodevelopmental assessment up to 5 years of corrected age using a Bayley Scales of Infant and Toddler Development or a Wechsler Preschool and Primary Scale of Intelligence. Parents were asked to complete several questionnaires.<h4>Main outcome measures</h4>Neurodevelopmental outcomes were measured. Mild delay was defined as -1 standard deviation (SD), 2021-01-01T00:00:00Z2021 Jan2025-05-31T23:03:08.876Z2025-05-31T23:03:08.876ZS-EPMC78184513198465210.1111/1471-0528.16115